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    E.g., 28/11/2024
    E.g., 28/11/2024
    3D reconstructions of superior (left) and inferior (right) brain regions, showing regions with lower metabolism associated with the presence of atherosclerotic plaques in the carotid arteries. The color code indicates the magnitude of the observation (yellow, strong association; red, lower association). Gray indicates areas showing no association with carotid plaque presence
    Research
    15 Feb 2021
    JACC: Spanish scientists uncover early links between cardiovascular risk and brain metabolism

    Among the modifiable cardiovascular risk factors showing a close association with reduced brain metabolism, the research team found that the most important is hypertension
    Manuel José Gómez, Ester Marina-Zárate, Almudena Ramiro, Ana Dopazo, Irene Fernández-Delgado, Francisco Sánchez-Madrid y Diego Calzada-Fraile
    Research
    3 Feb 2021
    Science Advances: Spanish scientists identify a mechanism through which dendritic cells improve their antiviral and immune-activation abilities

    Researchers at the CNIC have discovered that dendritic cells, which initiate specific immune responses, can reprogram their genes to improve their immune response
    Marta Amorós Pérez, Virginia Zorita, Nuria Matesanz, Marian Zuriaga y José Javier Fuster.
    About the CNIC
    23 Dec 2020
    CNIC to coordinate a European project investigating how cancer therapies promote atherosclerosis and cardiovascular disease

    The project will investigate the role of clonal hematopoiesis—the formation of mutated hematopoietic stem-cell clones promoted by anti-cancer therapies—in the development of atherosclerosis and associated cardiovascular disease
    Irene Fernández-Nueda, Carlos Cerón y Marta Cortés-Canteli
    About the CNIC
    15 Dec 2020
    CNIC scientists coordinate a European project to develop a biomarker for the early identification of the vascular component in Alzheimer disease

    The BioClotAD project, coordinated by CNIC scientist Dr Marta Cortés Canteli, has been selected by the EU Joint Programme – Neurodegenerative Disease Research (JPND)
    About the CNIC
    10 Dec 2020
    The 'ProtMechanics-Live' project, led by Dr. Jorge Alegre, awarded ERC Consolidator funding in the ERC-2020-COG call

    'ProtMechanics-Live' is based on unique expertise in protein mechanics and engineering, biophysics, biochemistry and cardiovascular biology and will allow to investigate protein mechanics for the first time in its functionally relevant physiological context
    About the CNIC
    10 Dec 2020
    'AngioUnrestUHD', led by Dr. Rui Benedito, awarded ERC Consolidator funding in the ERC-2020-COG call for proposals

    AngioUnrestUHD, will develop and apply new research tools and methods to advance knowledge about the biology of blood vessels in distinct physiological and pathological contexts
    De izda. a dcha.: Verónica Casquero, Sofía Sánchez, Irene García, Macarena Fernández, Wen Luo, Severin Muhleder, Lourdes García, Rui Benedito
    Research
    9 Dec 2020
    Nature: A new way to make arteries

    Científicos del CNIC han descubierto un mecanismo celular y molecular que puede ayudar a promover la arterialización y perfusión en los tejidos que han sufrido una reducción del riego sanguíneo.
    Research
    3 Dec 2020
    Science Advances: Spanish scientists identify the role of the CCT protein in the control of immune-synapse formation

    A new study published in  Science Advances identifies the role of the cytosolic chaperone protein CCT in the reorganization of the cytoskeleton during the formation of an immune synapse
    Jesús Vázquez, Almudena Ramiro, José Luis Martín Ventura, Inmaculada Martos Folgado, Cristina Lorenzo y Sonia Mur.
    Research
    2 Dec 2020
    Nature: CNIC scientists identify a new diagnostic and therapeutic target for cardiovascular disease

    Un estudio que se publica en Nature muestra a la proteína mitocondrial ALDH4A1 como un nuevo autoantígeno implicado en los procesos de la aterosclerosis
    Research
    27 Oct 2020
    Nature Cell Biology: Researchers identify a subgroup of stem cells that resists ageing and maintains muscle regeneration capacity until geriatric age

    The finding provides a basis for mitigating the loss of muscle regenerative capacity in very elderly people.