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    E.g., 05/07/2024
    E.g., 05/07/2024
    Research
    17 Sep 2020
    Nature Metabolism: CNIC researchers discover a mechanism allowing immune cells to regulate obesity

    The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes
    Research
    30 Jul 2020
    Science Advances: CNIC scientists discover the mechanism of competition between mitochondrial genomes coexisting in the same cell

    CNIC study shows that selection between mitochondrial genomes depends on how each type of mitochondria affects cell metabolism
    Research
    30 Jul 2020
    Nature: Scientists at the CNIC and IIS Princesa decipher a key mechanism in hypoxia

    The study, published in Nature, shows that sodium controls hypoxic signaling in the mitochondrial respiratory chain
    Alfonso Mora, María Elena Rodríguez Andrés, Guadalupe Sabio, Alejandro Rosell, Cintia Folgueira and Luis Leiva-Vega.
    Research
    30 Jun 2020
    PNAS: Scientists discover a new mechanism controlling liver cancer development

    CNIC scientists have designed an animal model to study the development of liver cancer caused by bile acids
    Research
    25 Jun 2020
    Science Advances: CNIC scientists identify the mechanism that regulates mitochondrial energy production

    The regulatory protein SCAF1 enables mitochondria to adapt to the available nutrient source of sugars, fats, or proteins
    Research
    4 Jun 2020
    Science Advances: CNIC scientists discover a system essential for limb formation during embryonic development

    Published in Science Advances, the study shows that malfunctioning of this system leads to congenital deformities
    Research
    29 May 2020
    Alejandro Sánchez Alvarado: "The real magic is to imagine the experiment and execute it"

    The researcher Alejandro Sánchez Alvarado is one of the greatest experts in the study of the mechanisms involved, cellular and biological, in regeneration in the planaria model
    Research
    28 Apr 2020
    Nature Communications: CNIC scientists design an experimental mouse model for investigating the mechanical function of proteins in vivo

    CNIC scientists, working with international partners, have developed a new experimental mouse model that allows them to study how cells sense, interpret, and generate mechanical forces
    Experimental design of the study and summary of the results obtained
    Research
    21 Apr 2020
    JACC: Spanish scientists identify a biomarker that detects atherosclerosis before the appearance of symptoms

    The study, published today in JACC, shows that activation of the complement system is one of the most characteristic molecular changes taking place in the early stages of the development of atherosclerotic plaques
    En la imagen se muestra con un asterisco la presencia de una placa de aterosclerosis avanzada en la carótida común detectada por la técnica de ecografía 3D que no llega a ocasionar una obstrucción significativa de la luz del vaso (es <50%). Se puede comprobar con precisión su extensión en las 3 dimensiones del espacio lo que nos permite detectar cambios en su volumen para determinar si existe un avance de la enfermedad.
    Research
    7 Apr 2020
    JACC: Atherosclerosis progresses rapidly in healthy people from the age of 40

    A CNIC study published in JACC demonstrates that atheroma plaques extend rapidly in the arteries of asymptomatic individuals aged between 40 and 50 years participating in the PESA-CNIC-Santander study.