Gene Regulation in Cardiovascular Remodelling and Inflammation Publications
Oller J*, Mendez-Barbero E*, Ruiz EJ, Villahoz S, Renard M, Canelas LI, Briones AM, Alberca R, Lozano-Vidal N, Hurle MA, Milewicz D, Evangelista A, Salaices M, Nistal JF, Jimenez-Borreguero LJ, De Backer J, Campanero MR*, Redondo JM*. (JO and NMB contributed equally, MRC and JMR are co-corresponding authors) Nitric oxide mediates aortic disease in mice deficient in the metalloprotease Adamts1 and in a mouse model of Marfan syndrome Nat Med (2017) 23:200-12
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de Carcer G, Wachowicz P, Martinez-Martinez S, Oller J, Mendez-Barbero N, Escobar B, Gonzalez-Loyola A, Takaki T, El Bakkali A, Camara JA, Jimenez-Borreguero LJ, Bustelo XR, Canamero M, Mulero F, de los Angeles Sevilla M, Montero MJ, Redondo JM*, Malumbres M*. (JMR and MM are co-corresponding authors) Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis. Nat Med (2017) 23:964-74
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Alvaro-Blanco J, Urso K, Chiodo Y, Martin-Cortazar C, Kourani O, Arco PG, Rodriguez-Martinez M, Calonge E, Alcami J, Redondo JM, Iglesias T, Campanero MR. MAZ induces MYB expression during the exit from quiescence via the E2F site in the MYB promoter. Nucleic Acids Res (2017) 45:9960-75
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Kurusamy S, Lopez-Maderuelo D, Little R, Cadagan D, Savage AM, Ihugba JC, Baggott RR, Rowther FB, Martinez-Martinez S, Arco PG, Murcott C, Wang W, Francisco Nistal J, Oceandy D, Neyses L, Wilkinson RN, Cartwright EJ, Redondo JM*, Armesilla AL*. (JMR and ALA are co-corresponding authors) Selective inhibition of plasma membrane calcium ATPase 4 improves angiogenesis and vascular reperfusion. J Mol Cell Cardiol (2017) 109:38-47
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Lopez-Santalla M, Mancheño-Corvo P, Escolano A, Menta R, DelaRosa O, Abad JL, Büscher D, Redondo JM, Bueren JA, Dalemans W, Lombardo E, Garin MI. Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis. Front Immunol (2017) 8:638
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Gómez-Del Arco P, Perdiguero E, Yunes-Leites PS, Acín-Pérez R, Zeini M, Garcia-Gomez A, Sreenivasan K, Jiménez-Alcázar M, Segalés J, López-Maderuelo D, Ornés B, Jiménez-Borreguero LJ, D'Amato G, Enshell-Seijffers D, Morgan B, Georgopoulos K, Islam AB, Braun T, de la Pompa JL, Kim J, Enriquez JA, Ballestar E, Muñoz-Cánoves P, Redondo JM The Chromatin Remodeling Complex Chd4/NuRD Controls Striated Muscle Identity and Metabolic Homeostasis Cell Metab (2016) 23:881-92
MacGrogan D, D'Amato G, Travisano S, Martinez-Poveda B, de Luxan G, Del Monte-Nieto G, Papoutsi T, Sbroggio M, Bou V, Gomez-Del Arco P, Gomez MJ, Zhou B, Redondo JM, Jimenez-Borreguero LJ, de la Pompa JL. Sequential Ligand-Dependent Notch Signaling Activation Regulates Valve Primordium Formation and Morphogenesis. Circ Res (2016) 118:1480-97
Gonzalez-Teran B, Lopez JA, Rodriguez E, Leiva L, Martinez-Martinez S, Bernal JA, Jimenez-Borreguero LJ, Redondo JM, Vazquez J, Sabio G. p38gamma and delta promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation. Nat Commun (2016) 7:10477
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Garcia-Quintans N, Sanchez-Ramos C, Prieto I, Tierrez A, Arza E, Alfranca A, Redondo JM, Monsalve M. Oxidative stress induces loss of pericyte coverage and vascular instability in PGC-1alpha-deficient mice. Angiogenesis (2016) 19:217-28
García-Marqués F, Trevisan-Herraz M, Martínez-Martínez S, Camafeita E, Jorge I, Lopéz JA, Méndez-Barbero N, Méndez-Ferrer S, Del Pozo MÁ, Ibáñez B, Andrés V, Sánchez-Madrid F, Redondo JM, Bonzon-Kulichenko E, Vázquez J. A novel systems-biology algorithm for the analysis of coordinated protein responses using quantitative proteomics Mol Cell Proteomics (2016) 15:1740-60