Análisis de muestras humanas y experimentos en animales demuestran que la presencia de mutaciones en el gen p53 en sangre aumenta el riesgo de desarrollar aterosclerosis, la principal causa de enfermedad cardiovascular.
Research, Publications

A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor

José Javier Fuster
About the CNIC, Publications

Researchers from the CNIC and Columbia University (USA) review the role of acquired mutations and clonal hematopoiesis in cardiovascular disease

Mª Ángeles Zuriaga, Mirian Díez, Fátima Sánchez-Cabo, Ana Dopazo, José Javier Fuster, Ana Quintas y Jorge de la Barrera.
Research, Publications

The study, carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia, establishes clonal hematopoiesis as a new cardiovascular risk factor and an important link between aging and cardiovascular disease


Marta Amorós Pérez, Virginia Zorita, Nuria Matesanz, Marian Zuriaga y José Javier Fuster.
About the CNIC, Research, Publications

The project will investigate the role of clonal hematopoiesis—the formation of mutated hematopoietic stem-cell clones promoted by anti-cancer therapies—in the development of atherosclerosis and associated cardiovascular disease