Selected publications

    Garcia-Gonzalez I, Rocha SF, Hamidi A, Garcia-Ortega L, Regano A, Sanchez-Muñoz MS, Lytvyn M, Garcia-Cabero A, Roig-Soucase S, Schoofs H, Castro M, Sabata H, Potente M, Graupera M, Makinen T, Benedito R. iSuRe-HadCre is an essential tool for effective conditional genetics. Nucleic Acids Res (2024) 52:gkae472
    Link to the full text in Repisalud
    Zarkada G, Chen X, Zhou X, Lange M, Zeng L, Lv W, Zhang X, Li Y, Zhou W, Liu K, Chen D, Ricard N, Liao J, Kim YB, Benedito R, Claesson-Welsh L, Alitalo K, Simons M, Ju R, Li X, Eichmann A, Zhang F. Chylomicrons Regulate Lacteal Permeability and Intestinal Lipid Absorption. Circ Res (2023) 133:333-349
    Link to the full text in Repisalud
    Fernández-Chacón M, Mühleder S, Regano A, Garcia-Ortega L, Rocha SF, Torroja C, Sanchez-Muñoz MS, Lytvyn M, , Casquero-Garcia V, De Andrés-Laguillo M, Muhl L, Orlich MM, Gaengel K, Camafeita E, Vazquez J, Benguría A, Iruela-Arispe ML, Dopazo A, Sánchez-Cabo F, Carter H, Benedito R. Incongruence between transcriptional and vascular pathophysiological cell states Nature Cardiovascular Research (2023) :1-38
    Link to the full text in Repisalud
    Garcia-Gonzalez I, Gambera S, Regano A, Rocha SF, Garcia-Ortega L, Lytvyn M, Sanchez-Muñoz MS, Garcia-Cabero A, Zagorac I, Luo W, Fernández-Chacón M, Casquero-Garcia V, Francesca Lunella F, Benedito, R. iFlpMosaics enable the multispectral barcoding and high-throughput comparative analysis of mutant and wildtype cells. bioRxiv (2023) Aug 29 [Epub ahead of print]
    bioRxiv
    Diago-Domingo L, Cuervo H, Benedito R. BMPing up endocardial angiogenesis to generate coronary vessels. Dev Cell (2022) 57:2515-2516
    Monelli E, Villacampa P, Zabala-Letona A, Martinez-Romero A, Llena J, Beiroa D, Gouveia L, Chivite I, Zagmutt S, Gama-Perez P, Osorio-Conles O, Muixi L, Martinez-Gonzalez A, Castillo SD, Martín-Martín N, Castel P, Valcarcel-Jimenez L, Garcia-Gonzalez I, Villena JA, Fernandez-Ruiz S, Serra D, Herrero L, Benedito R, Garcia-Roves P, Vidal J, Cohen P, Nogueiras R, Claret M, Carracedo A, Graupera M. Angiocrine polyamine production regulates adiposity. Nat Metab (2022) 4:327
    Link to the full text in Repisalud
    Bernier-Latmani J, Cisarovsky C, Mahfoud S, Ragusa S, Dupanloup I, Barras D, Renevey F, Nassiri S, Anderle P, Squadrito ML, Siegert S, Davanture S, González-Loyola A, Fournier N, Luther SA, Benedito R, Valet P, Zhou B, De Palma M, Delorenzi M, Sempoux C, Petrova TV. Apelin-driven endothelial cell migration sustains intestinal progenitor cells and tumor growth. Nature Cardiovascular Research (2022) 1:476
    Link to the full text in Repisalud
    Luo W, Garcia-Gonzalez I, Fernández-Chacón M, Casquero-Garcia V, Sanchez-Muñoz MS, Mühleder S, Garcia-Ortega L, Andrade J, Potente M, Benedito R Arterialization requires the timely suppression of cell growth Nature (2021) 589:437-441
    Mühleder S, Benedito R. An RNA helicase swirls in lymphangiogenesis Nat Cell Biol (2021) 23:1109-1110
    Mühleder S, Fernández-Chacón M, Garcia-Gonzalez I, Benedito R Endothelial sprouting, proliferation, or senescence: tipping the balance from physiology to pathology Cell Mol Life Sci (2021) 78:1329-54
    Fernández-Chacón M, García-González I, Mühleder S, Benedito R Role of Notch in endothelial biology Angiogenesis (2021) 24:237-50
    Garcia-Gonzalez I, Benedito R Intricacies of conditional genetics in vascular biology CURR OPIN HEMATOL (2021) 28:189-197
    Garcia-Gonzalez I, Mühleder S, Fernández-Chacón M, Benedito R Genetic Tools to Study Cardiovascular Biology Front Physiol (2020) 11:1084
    Link to the full text in Repisalud
    Lim R, Sugino T, Nolte H, Andrade J, Zimmermann B, Shi C, Doddaballapur A, Ong YT, Wilhelm K, Fasse JWD, Ernst A, Kaulich M, Husnjak K, Boettger T, Guenther S, Braun T, Kruger M, Benedito R, Dikic I, Potente M. Deubiquitinase USP10 regulates Notch signaling in the endothelium Science (2019) 364:188-193
    Link to the full text in Repisalud
    Pontes-Quero S, Fernandez-Chacón M, Lou W, Lunella FF, Casquero-Garcia V, Garcia-Gonzalez I, Hermoso A, Ferreira Rocha S, Bansal M, Benedito R High mitogenic stimulation arrests angiogenesis Nat Commun (2019) 10:2016
    Link to the full text in Repisalud
    Fernandez-Chacon M, Casquero-Garcia V, Lou W, Lunella FF, Ferreira Rocha S, Del Olmo-Cabrera S, Benedito R iSuRe-Cre is a genetic tool to reliably induce and report Cre-dependent genetic modifications Nat Commun (2019) 10:2262
    Link to the full text in Repisalud
    Pontes-Quero S, Heredia L, Casquero-Garcia V, Fernandez-Chacon M, Luo W, Hermoso A, Bansal M, Garcia-Gonzalez I, Sanchez-Munoz MS, Perea JR, Galiana-Simal A, Rodriguez-Arabaolaza I, Del Olmo-Cabrera S, Rocha SF, Criado-Rodriguez LM, Giovinazzo G, Benedito R. Dual ifgMosaic: A Versatile Method for Multispectral and Combinatorial Mosaic Gene-Function Analysis. Cell (2017) 170:800-14
    Link to the full text in Repisalud
    Rocha SF, Schiller M, Jing D, Li H, Butz S, Vestweber D, Biljes D, Drexler HC, Nieminen-Kelha M, Vajkoczy P, Adams S, Benedito R, Adams RH. Esm1 Modulates Endothelial Tip Cell Behavior and Vascular Permeability by Enhancing VEGF Bioavailability. Circ Res (2014) 115:581-90
    Benedito R, Rocha SF, Woeste M, Zamykal M, Radtke F, Casanovas O, Duarte A, Pytowski B, Adams RH. Notch-dependent VEGFR3 upregulation allows angiogenesis without VEGF-VEGFR2 signalling Nature (2012) 484:110-4
    Benedito R, Roca C, Sörensen I, Adams S, Gossler A, Fruttiger M, Adams RH. The notch ligands Dll4 and Jagged1 have opposing effects on angiogenesis Cell (2009) 137:1124-35

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