Selected publications

    Del Monte-Monge A, Martos-Folgado I, Rodríguez-Ronchel A, Ramiro AR. Assessing the impact of an antigen-specific antibody response on atherosclerosis development in mice. STAR Protoc (2023) 4:102274
    Link to the full text in Repisalud
    Raposo-Gutierrez I, Rodriguez-Ronchel A, Ramiro AR Atherosclerosis antigens as targets for immunotherapy Nature Cardiovascular Research (2023) :1129–1147
    Gómez-Escolar C, Serrano-Navarro A, Benguria A, Dopazo A, Sánchez-Cabo F, Ramiro AR. Single cell clonal analysis identifies an AID-dependent pathway of plasma cell differentiation. EMBO Rep (2022) 23
    Link to the full text in Repisalud
    Martos-Folgado I, Del Monte-Monge A, Lorenzo C, Busse CE, Delgado P, Mur SM, Cobos-Figueroa L, Escolà-Gil JC, Martín-Ventura JL, Wardemann H, Ramiro AR. MDA-LDL vaccination induces athero-protective germinal-center-derived antibody responses Cell Rep (2022) 41
    Link to the full text in Repisalud
    Lorenzo C, Delgado P, Busse CE, Sanz-Bravo A, Martos-Folgado I, Bonzon-Kulichenko E, Ferrarini A, Gonzalez-Valdes IB, Mur SM, Roldan-Montero R, Martinez-Lopez D, Martin-Ventura JL, Vazquez J, Wardemann H, Ramiro AR ALDH4A1 is an atherosclerosis auto-antigen targeted by protective antibodies Nature (2021) 589:287–292
    Link to the full text in Repisalud
    Alcaraz-Serna A, Bustos-Morán E, Fernández-Delgado I, Calzada-Fraile D, Torralba D, Marina-Zárate E, Lorenzo-Vivas E, Vázquez E, de Alburquerque JB, Ruef N, Gómez MJ, Sánchez-Cabo F, Dopazo A, Stein JV, Ramiro A, Sánchez-Madrid F Immune synapse instructs epigenomic and transcriptomic functional reprogramming in dendritic cells Sci Adv (2021) 7:eabb9965
    Fuertes T, Ramiro AR, de Yebenes VG miRNA-Based Therapies in B Cell Non-Hodgkin Lymphoma Trends Immunol (2020) 41:932-947
    Link to the full text in Repisalud
    Delgado P, Alvarez-Prado AF, Marina-Zarate E, Sernandez IV, Mur SM, de la Barrera J, Sanchez-Cabo F, Canamero M, de Molina A, Belver L, de Yebenes VG, Ramiro AR Interplay between UNG and AID governs intratumoral heterogeneity in mature B cell lymphoma PLoS Genet (2020) 16:e1008960
    de Yebenes VG, Briones AM, Martos-Folgado I, Mur SM, Oller J, Bilal F, Gonzalez-Amor M, Mendez-Barbero N, Silla-Castro JC, Were F, Jimenez-Borreguero LJ, Sanchez-Cabo F, Bueno H, Salaices M, Redondo JM, Ramiro AR Aging-Associated miR-217 Aggravates Atherosclerosis and Promotes Cardiovascular Dysfunction Arterioscler Thromb Vasc Biol (2020) 40:2408-2424
    Alvarez-Prado AF, Perez-Duran P, Perez-Garcia A, Benguria A, Torroja C, de Yebenes VG, Ramiro AR. A broad atlas of somatic hypermutation allows prediction of activation-induced deaminase targets. J Exp Med (2018) 215:761-771
    Link to the full text in Repisalud
    Bartolome-Izquierdo N, De Yebenes VG, Alvarez-Prado AF, Mur SM, Lopez JA, Roa S, Vazquez J, Ramiro AR. miR-28 regulates the germinal center reaction and blocks tumor growth in preclinical models of non-Hodgkin lymphoma. Blood (2017) 129:2408-19
    Link to the full text in Repisalud
    Pérez-García A, Marina-Zárate E, Álvarez-Prado ÁF, Ligos JM, Galjart N, Ramiro AR. CTCF orchestrates the germinal centre transcriptional program and prevents premature plasma cell differentiation. Nat Commun (2017) 8:16067
    Perez-Garcia A, Perez-Duran P, Wossning T, Sernandez IV, Mur SM, Canamero M, Real FX, Ramiro AR. AID-expressing epithelium is protected from oncogenic transformation by an NKG2D surveillance pathway. EMBO Mol Med (2015) 7:1327-36
    Link to the full text in Repisalud
    de Yebenes VG, Bartolome-Izquierdo N, Nogales-Cadenas R, Perez-Duran P, Mur SM, Martinez N, Di Lisio L, Robbiani DF, Pascual-Montano A, Canamero M, Piris MA and Ramiro AR. miR-217 is an oncogene that enhances the germinal center reaction. Blood (2014) 124:229-39
    de Yébenes VG, Bartolomé-Izquierdo N, Ramiro AR. Regulation of B-cell development and function by microRNAs. Immunol Rev (2013) 253:25-39
    Pérez-Durán P, Belver L, de Yébenes VG, Delgado P, Pisano DG, Ramiro AR. UNG shapes the specificity of AID-induced somatic hypermutation. J Exp Med (2012) 209:1379-89
    Belver L, Papavasiliou FN, Ramiro AR. MicroRNA control of lymphocyte differentiation and function. Curr Opin Immunol (2011) 23:369-73
    Belver L, de Yébenes VG, Ramiro AR. MicroRNAs prevent the generation of autoreactive antibodies. Immunity (2010) 33:713-22
    de Yebenes VG, Belver L, Pisano DG, Gonzalez S, Villasante A, Croce C, He L, Ramiro AR. miR-181b negatively regulates activation-induced cytidine deaminase in B cells. J Exp Med (2008) 205:2199-206
    Ramiro AR, Jankovic M, Callen E, Difilippantonio S, Chen HT, McBride KM, Eisenreich TR, Chen J, Dickins RA, Lowe SW, Nussenzweig A, Nussenzweig MC. Role of genomic instability and p53 in AID-induced c-myc-Igh translocations. Nature (2006) 440:105-9

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