Selected publications

    Lalaguna L, Arévalo-Núñez de Arenas M, López-Olañeta M, Villalba-Orero M, Jiménez-Riobóo RJ, Gómez-Gaviro MV, Isern J, Muñoz-Cánoves P, Byrne BJ, Ochoa JP, García-Pavía P, Lara-Pezzi E. Overexpression of Wild-Type TMEM43 Improves Cardiac Function in Arrhythmogenic Right Ventricular Cardiomyopathy Type 5. Circ Res (2025) 136:830-84
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    Díez-Díez M, Ramos-Neble BL, de la Barrera J, Silla-Castro JC, Quintas A, Vázquez E, Rey-Martín MA, Izzi B, Sánchez-García L, García-Lunar I, Mendieta G, Mass V, Gómez-López N, Espadas C, González G, Quesada AJ, García-Álvarez A, Fernández-Ortiz A, Lara-Pezzi E, Dopazo A, Sánchez-Cabo F, Ibáñez B, Andrés V, Fuster V, Fuster JJ. Unidirectional association of clonal hematopoiesis with atherosclerosis development. Nat Med (2024) 30:2857-2866
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    Cañas-Alvaro R, Lalaguna L, Rubio B, Ausiello A, López-Olañeta M, Serrano-Blanco RF, Ochoa JP, de la Pompa JL, Chavez A, García-Pavía P, Lara-Pezzi E. CRISPR activation to repair electrocardiogram abnormalities caused by a FLNC truncating variant in mice. Eur Heart J (2024) 46:4610-4613
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    Villalba-Orero M, López-Olañeta M, Campos-Olmo B, Jimenez-Carretero D, Sánchez L, Sánchez-Cabo F, Ausiello A, Cañas-Álvaro R, Camafeita E, Vázquez J, García-Pavía P, Pascual-Figal D, Lara-Pezzi E. Unraveling Comorbidities Contribution to Cardiac Diastolic Dysfunction and Heart Failure. Circ Heart Fail (2024) 18:e011724
    Sánchez-Cabo F, Fuster V, Silla-Castro JC, González G, Lorenzo-Vivas E, Alvarez R, Callejas S, Benguría A, Gil E, Núñez E, Oliva B, Mendiguren JM, Cortes-Canteli M, Bueno H, Andrés V, Ordovás JM, Fernández-Friera L, Quesada AJ, Garcia JM, Rossello X, Vázquez J, Dopazo A, Fernández-Ortiz A, Ibáñez B, Fuster JJ, Lara-Pezzi E. Subclinical atherosclerosis and accelerated epigenetic age mediated by inflammation: a multi-omics study. Eur Heart J (2023) 4:2698-2709
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    Villalba-Orero M, Garcia-Pavia P, Lara-Pezzi E. Non-invasive assessment of HFpEF in mouse models: current gaps and future directions. BMC Med (2022) 20
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    Martí-Gómez C, Larrasa-Alonso J, López-Olañeta M, Villalba-Orero M, García-Pavía P, Sánchez-Cabo F, Lara-Pezzi E. Functional Impact and Regulation of Alternative Splicing in Mouse Heart Development and Disease. J Cardiovasc Transl Res (2022) 15:1239-1255
    Groun N, Villalba-Orero M, Lara-Pezzi E, Valero E, Garicano-Mena J, Le Clainche S. A novel data-driven method for the analysis and reconstruction of cardiac cine MRI. Comput Biol Med (2022) 151:106317
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    Larrasa-Alonso J, Villalba M, Martí-Gómez C, Ortiz-Sánchez P, López-Olañeta M, Rey-Martin MA, Sanchez-Cabo F, McNicoll F, Müller-McNicoll M, Garcia-Pavia P, Lara-Pezzi E The SRSF4-GAS5-Glucocorticoid Receptor Axis Regulates Ventricular Hypertrophy Circ Res (2021) 129:669-683
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    Sanchez-Cabo F, Rossello X, Fuster V, Benito F, Manzano JP, Silla JC, Fernandez-Alvira JM, Oliva B, Fernandez-Friera L, Lopez-Melgar B, Mendiguren JM, Sanz J, Ordovas JM, Andres V, Fernandez-Ortiz A, Bueno H, Ibanez B, Garcia-Ruiz JM, Lara-Pezzi E Machine Learning Improves Cardiovascular Risk Definition for Young, Asymptomatic Individuals J Am Coll Cardiol (2020) 76:1674-1685
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    Dominguez F, Zorio E, Jimenez-Jaimez J, Salguero-Bodes R, Zwart R, Gonzalez-Lopez E, Molina P, Bermudez-Jimenez F, Delgado JF, Braza-Boils A, Bornstein B, Toquero J, Segovia J, Van Tintelen JP, Lara-Pezzi E*, Garcia-Pavia P* (ELP and PGP are co-correspondig authors) Clinical characteristics and determinants of phenotype in TMEM43 Arrhythmogenic right ventricular cardiomyopathy type 5 Heart Rhythm (2020) 17:945-954
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    Marti-Gomez C, Lara-Pezzi E*, Sanchez-Cabo F* (ELP and FSC are co-corresponding authors) dSreg: A Bayesian model to integrate changes in splicing and RNA binding protein activity Bioinformatics (2020) 36:2134-2141
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    Garcia-Pavia P, Kim Y, Alejandra Restrepo-Cordoba M, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nunez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, Baksi AJ, O'Regan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE Genetic Variants Associated with Cancer Therapy-Induced Cardiomyopathy Circulation (2019) 140:31-41
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    Padron-Barthe L, Villalba-Orero M, Gomez-Salinero JM, Dominguez F, Roman M, Larrasa-Alonso J, Ortiz-Sanchez P, Martinez F, Lopez-Olaneta M, Bonzon-Kulichenko E, Vazquez J, Marti-Gomez C, Santiago DJ, Prados B, Giovinazzo G, Gomez-Gaviro MV, Priori S, Garcia-Pavia P, Lara-Pezzi E Severe Cardiac Dysfunction and Death Caused by Arrhythmogenic Right Ventricular Cardiomyopathy Type 5 Are Improved by Inhibition of Glycogen Synthase Kinase-3beta Circulation (2019) 140:1188-1204
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    Ortiz-Sanchez P, Villalba-Orero M, Lopez-Olaneta MM, Larrasa-Alonso J, Sanchez-Cabo F, Marti-Gomez C, Camafeita E, Gomez-Salinero JM, Ramos-Hernandez L, Nielsen PJ, Vazquez J, Muller-McNicoll M, Garcia-Pavia P, Lara-Pezzi E Loss of SRSF3 in Cardiomyocytes Leads to Decapping of Contraction Related mRNAs and Severe Systolic Dysfunction Circ Res (2019) 125:170-183
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    Padron-Barthe L, Villalba-Orero M, Gomez-Salinero J, Acin-Perez R, Cogliati S, Lopez-Olaneta M, Ortiz-Sanchez P, Bonzon-Kulichenko E, Vazquez J, Garcia-Pavia P, Rosenthal N, Enriquez JA, Lara-Pezzi E. Activation of Serine One-Carbon Metabolism by Calcineurin Aβ1 Reduces Myocardial Hypertrophy and Improves Ventricular Function. J Am Coll Cardiol (2018) 71:654-67
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    Villalba-Orero M, Sanchez-Elexpuru G, Lopez-Olaneta M, Campuzano O, Bello-Arroyo E, Garcia-Pavia P, Serratosa JM, Brugada R, Sanchez MP, Lara-Pezzi E. Lafora Disease Is an Inherited Metabolic Cardiomyopathy. J Am Coll Cardiol (2017) 69:3007-9
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    Amor-Salamanca A, Castillo S, Gonzalez-Vioque E, Dominguez F, Quintana L, Lluis-Ganella C, Escudier JM, Ortega J, Lara-Pezzi E, Alonso-Pulpon L, Garcia-Pavia P. Genetically Confirmed Familial Hypercholesterolemia in Patients With Acute Coronary Syndrome. J Am Coll Cardiol (2017) 70:1732-40
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    Villalba-Orero M, Lopez-Olaneta MM, Gonzalez-Lopez E, Padron-Barthe L, Gomez-Salinero JM, Garcia-Prieto J, Wai T, Garcia-Pavia P, Ibanez B, Jimenez-Borreguero LJ, Lara-Pezzi E. Lung ultrasound as a translational approach for non-invasive assessment of heart failure with reduced or preserved ejection fraction in mice. Cardiovasc Res (2017) 113:1113-23
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    Padron-Barthe L, Dominguez F, Garcia-Pavia P, Lara-Pezzi E. Animal models of arrhythmogenic right ventricular cardiomyopathy: what have we learned and where do we go? Insight for therapeutics. Basic Res Cardiol (2017) 112:50
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