Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research, Publications
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart

    About the CNIC, Research, Publications
    The 'ProtMechanics-Live' project, led by Dr. Jorge Alegre, awarded ERC Consolidator funding in the ERC-2020-COG call

    'ProtMechanics-Live' is based on unique expertise in protein mechanics and engineering, biophysics, biochemistry and cardiovascular biology and will allow to investigate protein mechanics for the first time in its functionally relevant physiological context

    About the CNIC, Research, Publications
    El proyecto 'ProtMechanics-Live', del Dr. Jorge Alegre, seleccionado dentro de ‘ERC Consolidator’ en la convocatoria ERC-2020-COG

    'ProtMechanics-Live' se basa en la experiencia única en mecánica e ingeniería de proteínas, biofísica, bioquímica y biología cardiovascular y permitirá investigar la mecánica de proteínas por primera vez en su contexto fisiológico funcionalmente relevante

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