Selected publications

Al-Mashhadi RH, Al-Mashhadi AL, Nasr ZP, Mortensen MB, Lewis EA, Camafeita E, Ravlo K, Al-Mashhadi Z, Kjær DW, Palmfeldt J, Bie P, Jensen JM, Nørgaard BL, Falk E, Vázquez J, Bentzon JF Local Pressure Drives Low-Density Lipoprotein Accumulation and Coronary Atherosclerosis in Hypertensive Minipigs J Am Coll Cardiol (2021) 77:575-89

Martos-Rodríguez CJ, Albarrán-Juárez J, Morales-Cano D, Caballero A, MacGrogan D, de la Pompa JL, Carramolino L, Bentzon JF Fibrous Caps in Atherosclerosis Form by Notch-Dependent Mechanisms Common to Arterial Media Development Arterioscler Thromb Vasc Biol (2021) 41:e427-e439

Nogales P, Velasco C, Mota-Cobián A, González-Cintado L, Mota RA, España S, Mateo J, Bentzon JF Analysis of (18)F-Sodium Fluoride Positron Emission Tomography Signal Sources in Atherosclerotic Minipigs Shows Specific Binding of (18)F-Sodium Fluoride to Plaque Calcifications Arterioscler Thromb Vasc Biol (2021) 41:e480-e490

Al-Mashhadi RH, Tolbod LP, Bloch LO, Bjorklund MM, Nasr ZP, Al-Mashhadi Z, Winterdahl M, Frokiaer J, Falk E, Bentzon JF (18)Fluorodeoxyglucose Accumulation in Arterial Tissues Determined by PET Signal Analysis J Am Coll Cardiol (2019) 74:1220-32
Link to the full text in Repisalud

Bentzon JF, Majesky MW. Lineage tracking of origin and fate of smooth muscle cells in atherosclerosis. Cardiovasc Res (2018) 114:492-500
Link to the full text in Repisalud

Hagensen MK, Mortensen MB, Kjolby M, Stillits NL, Steffensen LB, Bentzon JF. Type 1 diabetes increases retention of low-density lipoprotein in the atherosclerosis-prone area of the murine aorta. Atherosclerosis (2017) 263:7-14
Link to the full text in Repisalud

Jacobsen K, Lund MB, Shim J, Gunnersen S, Fuchtbauer EM, Kjolby M, Carramolino L, Bentzon JF. Diverse cellular architecture of atherosclerotic plaque derives from clonal expansion of a few medial SMCs. JCI Insight (2017) 2:95890
Link to the full text in Repisalud

Shim J, Poulsen CB, Hagensen MK, Larsen T, Heegaard PMH, Christoffersen C, Bolund L, Schmidt M, Liu Y, Li J, Li R, Callesen H, Bentzon JF, Sørensen CB. Apolipoprotein E Deficiency Increases Remnant Lipoproteins and Accelerates Progressive Atherosclerosis, But Not Xanthoma Formation, in Gene-Modified Minipigs. JACC Basic Transl Sci (2017) 2:591-600
Link to the full text in Repisalud

Bentzon JF. Targeting Inflammation in Atherosclerosis. J Am Coll Cardiol (2016) 68:2794-6

Shim J, Al-Mashhadi RH, Sorensen CB, Bentzon JF. Large animal models of atherosclerosis - new tools for persistent problems in cardiovascular medicine. J Pathol (2016) 238:257-66

Steffensen LB, Mortensen MB, Kjolby M, Hagensen MK, Oxvig C, Bentzon JF. Disturbed Laminar Blood Flow Vastly Augments Lipoprotein Retention in the Artery Wall: A Key Mechanism Distinguishing Susceptible From Resistant Sites. Arterioscler Thromb Vasc Biol (2015) 35:1928-35

Mortensen MB, Kjolby M, Gunnersen S, Larsen JV, Palmfeldt J, Falk E, Nykjaer A, Bentzon JF Targeting sortilin in immune cells reduces proinflammatory cytokines and atherosclerosis J Clin Invest (2014) 124:5317-22

Bentzon JF, Otsuka F, Virmani R, Falk E Mechanisms of plaque formation and rupture Circ Res (2014) 114:1852-66

Bjørklund MM, Hollensen AK, Hagensen MK, Dagnaes-Hansen F, Christoffersen C, Mikkelsen JG, Bentzon JF Induction of atherosclerosis in mice and hamsters without germline genetic engineering Circ Res (2014) 114:1684-9

Al-Mashhadi RH, Sørensen CB, Kragh PM, Christoffersen C, Mortensen MB, Tolbod LP, Thim T, Du Y, Li J, Liu Y, Moldt B, Schmidt M, Vajta G, Larsen T, Purup S, Bolund L, Nielsen LB, Callesen H, Falk E, Mikkelsen JG, Bentzon JF Familial hypercholesterolemia and atherosclerosis in cloned minipigs created by DNA transposition of a human PCSK9 gain-of-function mutant Sci Transl Med (2013) 5:166ral