Selected publications

    Zeng Q, Oliva VM, Moro MÁ, Scheiermann C. Circadian Effects on Vascular Immunopathologies. Circ Res (2024) 134:791-809.
    Link to the full text in Repisalud
    Semerano A, Fernández-Ruiz J, Cortes-Canteli M, Moro MA. From Alzheimer's disease to vascular dementia: Different roads leading to cognitive decline. Br J Pharmacol (2024) 181:755-759
    Link to the full text in Repisalud
    Di G, Vazquez S, Díaz B, Peña-Martinez C, García-Culebras A, Cuartero MI, Moraga A, Pradillo JM, Esposito E, Lo EH, Moro MA*, Lizasoain I* Daytime DNase-I administration protects mice from ischemic stroke without inducing bleeding or tPA-induced hemorrhagic transformation, even with aspirin pretreatment. Stroke (2024) Dec 15 [Epub ahead of print]
    Torres-López C, Cuartero MI, García-Culebras A, de la Parra J, Fernández-Valle ME, Benito M, Vázquez-Reyes S, Jareño-Flores T, de Castro-Millán FJ, Hurtado O, Buckwalter MS, García-Segura JM, Lizasoain I, Moro MA. Ipsilesional Hippocampal GABA Is Elevated and Correlates With Cognitive Impairment and Maladaptive Neurogenesis After Cortical Stroke in Mice. Stroke (2023) 54:2652-2665
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    Fraga E, Medina V, Cuartero MI, García-Culebras A, Bravo-Ferrer I, Hernández-Jiménez M, Garcia-Segura JM, Hurtado O, Pradillo JM, Lizasoain I, Moro MÁ. Defective hippocampal neurogenesis underlies cognitive impairment by carotid stenosis-induced cerebral hypoperfusion in mice. Front Cell Neurosci (2023) 17:1219847
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    Hernández-Jiménez M, Abad-Santos F, Cotgreave I, Gallego J, Jilma B, Flores A, Jovin TG, Vivancos J, Hernández-Pérez M, Molina CA, Montaner J, Casariego J, Dalsgaard M, Liebeskind DS, Cobo E, Castellanos M, Portela PC, Masjuán J, Moniche F, Tembl JI, Terceño Izaga M, Arenillas JF, Callejas P, Olivot JM, Calviere L, Henon H, Mazighi M, Piñeiro D, Pugliese M, González VM, Moro MA, Garcia-Tornel A, Lizasoain I, Ribo M. Safety and Efficacy of ApTOLL in Patients With Ischemic Stroke Undergoing Endovascular Treatment: A Phase 1/2 Randomized Clinical Trial. JAMA Neurol (2023) 80:779-788.
    Endres M, Moro MA, Nolte CH, Dames C, Buckwalter MS, Meisel A. Immune Pathways in Etiology, Acute Phase, and Chronic Sequelae of Ischemic Stroke Circ Res (2022) 130:1167-1186
    Li W, Mandeville ET, Durán-Laforet V, Fukuda N, Yu Z, Zheng Y, Held A, Park JH, Nakano T, Tanaka M, Shi J, Esposito E, Niu W, Xing C, Hayakawa K, Lizasoain I, van Leyen K, Ji X, Wainger BJ, Moro MA, Lo EH. Endothelial cells regulate astrocyte to neural progenitor cell trans-differentiation in a mouse model of stroke Nat Commun (2022) 13:7812
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    Esposito E, Zhang F, Park JH, Mandeville ET, Li W, Cuartero MI, Lizasoaín I, Moro MA, Lo EH. Diurnal Differences in Immune Response in Brain, Blood and Spleen After Focal Cerebral Ischemia in Mice Stroke (2022) 53:e507-e511
    Link to the full text in Repisalud
    Hernández-Jiménez M, Martín-Vílchez S, Ochoa D, Mejía-Abril G, Román M, Camargo-Mamani P, Luquero-Bueno S, Jilma B, Moro MA, Fernández G, Piñeiro D, Ribó M, González VM, Lizasoain I, Abad-Santos F. First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers. Mol Ther Nucleic Acids (2022) 9:124-135
    Link to the full text in Repisalud
    Tiedt S, Buchan AM, Dichgans M, Lizasoain I, Moro MA, Lo EH. The neurovascular unit and systemic biology in stroke - implications for translation and treatment. Nat Rev Neurol (2022) 18:597-612
    McCullough LD, Moro MA Translational Interdisciplinary Science-Immune Cell Niches: Possible Targets for Stroke Therapy? Stroke (2021) 52:3692-3695
    Adrover JM, del Fresno C, Crainiciuc G, Cuartero MI, Casanova-Acebes M, Weiss LA, Huerga-Encabo H, Silvestre-Roig C, Rossaint J, Cossío I, Lechuga-Vieco AV, García-Prieto J, Gómez-Parrizas M, Quintana JA, Ballesteros I, Martin-Salamanca S, Aroca-Crevillen A, Chong SZ, Evrard M, Balabanian K, López J, Bidzhekov K, Bachelerie F, Abad-Santos F, Muñoz-Calleja C, Zarbock A, Soehnlein O, Weber C, Ng LG, Lopez-Rodriguez C, Sancho D, Moro MA, Ibanez B, Hidalgo A. A Neutrophil Timer Coordinates Immune Defense and Vascular Protection. Immunity (2019) 50:390-402
    Link to the full text in Repisalud
    Cuartero MI, de la Parra J, Pérez-Ruiz A, Bravo-Ferrer I, Durán-Laforet V, García-Culebras A, García-Segura JM, Dhaliwal J, Frankland PW, Lizasoain I, Moro MA Abolition of aberrant neurogenesis ameliorates cognitive impairment after stroke in mice J Clin Invest (2019) 129:1536-50
    Peña-Martínez C, Durán-Laforet V, García-Culebras A, Ostos F, Hernández-Jiménez M, Bravo-Ferrer I, Pérez-Ruiz A, Ballenilla F, Díaz-Guzmán J, Pradillo JM, Lizasoain I, Moro MA Pharmacological Modulation of Neutrophil Extracellular Traps Reverses Thrombotic Stroke tPA (Tissue-Type Plasminogen Activator) Resistance. Stroke (2019) 50:3228-3237
    Bravo-Ferrer I, Cuartero MI, Medina V, Ahedo-Quero D, Peña-Martínez C, Pérez-Ruíz A, Fernández-Valle ME, Hernández-Sánchez C, Fernández-Salguero PM, Lizasoain I, Moro MA. Lack of the aryl hydrocarbon receptor accelerates aging in mice FASEB J (2019) 33:12644-54
    Sreeramkumar V, Adrover JM, Ballesteros I, Cuartero MI, Rossaint J, Bilbao I, Nácher M, Pitaval C, Radovanovic I, Fukui Y, McEver RP, Filippi M-D, Lizasoain I, Ruiz-Cabello J, Zarbock A, Moro MA, Hidalgo A Neutrophils scan for activated platelets to initiate inflammation Science (2014) 346:1234-8
    Cuartero MI, Ballesteros I, Parra J, Harkin AL, Abautret-Daly A, Fernández-Salguero P, Corbí AL, Lizasoain I, Moro MA Deleterious role of the aryl hydrocarbon receptor and its agonist l-kynurenin in acute ischemic brain damage Circulation (2014) 130:2040-51
    Morales JR, Ballesteros I, Deniz JM, Hurtado O, Vivancos J, Nombela F, Lizasoain I, Castrillo A, Moro MA Activation of liver X receptors promotes neuroprotection and reduces brain inflammation in experimental stroke Circulation (2008) 118:1450-9
    Caso JR, Pradillo JM, Hurtado O, Lorenzo P, Moro MA, Lizasoain I Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke Circulation (2007) 115:1599-608

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