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    E.g., 03/04/2025
    E.g., 03/04/2025
    Enrique Lara-Pezzi, Laura Lalaguna, Benedetta Coppe, Nadia Mercader y María Galardi-Castilla.
    Research
    2 Apr 2025
    Circulation: The heart remembers: scientists describe how early-life cardiac injury in parents influences the development and function of the heart in the next generation

    Scientists at the CNIC and the University of Bern have found that heart surgery in male mice early in life creates a "memory" passed down to the next generation. Published in Circulation, the study suggests that a parental history of heart surgery should be considered when evaluating cardiovascular health in descendants.
    About the CNIC
    18 Mar 2025
    CNIC joins GRACE, a European project aimed at transforming cardiovascular care through innovation and collaboration

    The CNIC has been allocated €405,625 for its involvement in GRACE, a project focused on developing innovative strategies to improve the detection and management of cardiovascular diseases.
    Dr. Fuster
    About the CNIC
    17 May 2024
    Dr Valentín Fuster receives the AstraZeneca Foundation Honorific Award for Excellence in Scientific Research
    Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
    Research
    29 Nov 2022
    Basic Research in Cardiology: A new therapeutic target for the prevention of heart failure due to aortic stenosis

    The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart
    Descubren un factor clave que protege el corazón tras un infarto
    About the CNIC
    2 Nov 2022
    JCI: CNIC scientists identify a factor that protects the heart against damage after a heart attack

    A new study defines a mechanism that regulates inflammation after a myocardial infarction, opening a path to the use of the receptor

    Fernando de Frutos y el Dr. Pablo García Pavía.
    Research
    29 Aug 2022
    JACC: CNIC scientists describe key features of one of the most frequent forms of hereditary dilated cardiomyopathy

    The findings, published in the Journal of the American College of Cardiology (JACC), represent a first step towards the personalized treatment of patients with this disease
    Valentín Fuster
    Research
    26 Aug 2022
    NEJM: The polypill reduces cardiovascular mortality by 33% in patients treated after myocardial infarction

    The results of the SECURE trial, coordinated by CNIC were presented in a Hot Line session at the European Society of Cardiology meeting (ESC 2022) in Barcelona and published at the NEJM

    Miguel Palomino Segura, Georgiana Crainiciuc, Jon Sicilia y Andrés Hidalgo
    Research
    5 Jan 2022
    Nature: CNIC scientists discover a cell behavior pattern that predicts cardiovascular disease

    Scientists at the CNIC have developed a simple model for studying the behavior of immune cells in live animals and have identified a harmful cell behavior pattern associated with cardiovascular disease
    Representative transmurality map from an 3D-upsampled model with a short axis view at high-magnification to illustrate the 3D methodology for transmural-based scar assessment from images obtained with conventional 2D delayed gadolinium-enhanced CMR
    Research
    28 Sep 2021
    Scientific Reports: 3D mapping of post-infarction scarring increases the prognostic potential of cardiac magnetic resonance imaging

    This innovative technology may provide an efficient approach in clinical practice after manual or automatic segmentation of myocardial borders in a small number of conventional 2D slices and automatic scar detection
    About the CNIC
    6 Aug 2021
    RREBOOT, on a mission to change clinical practice guidelines for the treatment of heart attack survivors

    CNIC and the Mario Negri Institute in Milan (Italy) coordinate REBOOT, a project that aims to study whether treatment with beta-blockers is beneficial for patients who have suffered a myocardial infarction