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E.g., 24/11/2024
E.g., 24/11/2024
Dr. Pablo García-Pavía y Dr. Jesús Gonzalez Mirelis, codirectores del trabajo.
Research
22 Jul 2022

Genetic screening combined with the detection of fibrosis identifies patients at risk of malignant arrhythmias or developing heart failure with severe complications


Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
Research
29 Jun 2022

Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”

An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
Research
17 May 2022

The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart

From left to right: Claudio Badía Careaga, Jesús Vázquez, Enrique Calvo, Elías Herrero Galán, Natalia Vicente, Jorge Alegre Cebollada, Inés Martínez Martín, Carmen Suay Corredera, Diana Velázquez Carreras y Maria Rosaria Pricolo.
Research
27 Apr 2022

The results, published in Redox Biology, show the role of conserved cysteine residues in the elastic protein titin in the modulation of the mechanical properties of the myocardium

Rebeca Piñeiro, Joaquim Grego-Bessa, Vitor Samuel Leite, Luis luna-Zurita
Research
12 Nov 2021

A study published in Science Advances shows that the gene GPR126, while not required for the development of the heart, plays an essential role in the formation of the placenta, the gestational organ that nourishes the fetus

Daño local en las fibras musculares tras el ejercicio. Visualización del daño local en fibras de músculo esquelético (soleous y gastro) de ratón joven tras el ejercicio, mediante la tinción con marcadores de daño local como Filamina C (verde) y Evans Blue (rojo), y los núcleos (en azul) de fibras.
Research
18 Oct 2021

Researchers from the National Center for Cardiovascular Research and the Pompeu Fabra University describe in Science a new mechanism for muscle regeneration after physiological damage

About the CNIC
6 Aug 2021

CNIC and the Mario Negri Institute in Milan (Italy) coordinate REBOOT, a project that aims to study whether treatment with beta-blockers is beneficial for patients who have suffered a myocardial infarction

Grupo de la Dra. Priori
Research
21 Jul 2021

The research team led by project leader Dr Silvia Priori is confident that the discovery of new therapies will reduce the mortality linked to this disease and could also reduce arrhythmias in heart failure patients

Imagen
About the CNIC
29 Jun 2021

 Over one million European cancer patients suffer from side effects to chemotherapy

Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
Research
7 Jun 2021

A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart