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E.g., 23/11/2024
E.g., 23/11/2024
Dr. García Pavía
Research
21 May 2023

The team led by Dr. Pablo García-Pavía, based at the CNIC and Hospital Puerta de Hierro, has published the first study of a drug able to remove amyloid deposits from the heart

Imágenes del corazón obtenidas mediante resonancia magnética en las que se analizan distintas estructuras de la anatomía y función del corazón: aurículas (paneles A y B), ventrículos (paneles C y D), características del tejido cardiaco (paneles E y F).
Research
3 Mar 2023

The results, published in eClinicalMedicine, have direct implications for clinical practice by providing a list of reference values for a multitude of cardiac parameters used in daily practice

Cells use two mechanisms to detect force: one gradual and progressive mediated by newly identified large membrane depressions called dolines (left); the other abrupt, activated above a certain threshold, and mediated by minute membrane invaginations called caveolae (right).
Research
23 Dec 2022

A study published in Nature Cell Biology confirms that caveolae are essential for the mechanical responses of tissues subject to large mechanical forces (such as muscle, heart, blood vessels, and fat), whereas larger membrane depressions (termed 'dolines') are important for the response to weak or medium-strength forces

Las células senescentes (mostradas por luminiscencia) aparecieron en el hombro de ratón después de la lesión
Research
19 Dec 2022

The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people and for improving muscle repair in young healthy people

La figura muestra imágenes mediante resonancia magnética cardíaca (A y B) y tomografía computarizada (C y D) de un corazón en diástole (A y C) y sístole (B y D) para el cálculo de la función de ambos ventrículos. VD: Ventrículo derecho; VI: Ventrículo izquierdo.
Research
12 Dec 2022

The results of the SPHERE-HF study are published in the European Journal of Heart Failure. SPHERE-HF is a multicenter academic clinical trial led by investigators at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Hospital Clínic de Barcelona

Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
Research
29 Nov 2022

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

Research
3 Nov 2022

CNIC scientists have identified a molecular mechanism that accounts for the arrhythmias, skeletal muscle weakness, and periodic paralysis in patients with this rare disease

Descubren un factor clave que protege el corazón tras un infarto
About the CNIC
2 Nov 2022

A new study defines a mechanism that regulates inflammation after a myocardial infarction, opening a path to the use of the receptor

About the CNIC
23 Aug 2022

The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people

Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
Research
26 Jul 2022

Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals