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Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), together with cardiologists from Hospital Universitario Puerta de Hierro and the Spanish cardiovascular disease research network (CIBERCV), report that the new discovery makes it possible to identify high-risk patients early and refer them sooner to specialized heart failure units

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances

The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer

A CNIC study reveals that mutations previously identified in the gene MINDBOMB1 (MIB1) as causing non-compaction cardiomyopathy either provoke this disease or valve defects, depending on their combination with mutations in modifier genes

A study published in Hepatology demonstrates that the activation of thermogenesis in the livers of obese mice contributes to weight loss and improves diabetes symptoms

Researchers at the CNIC have discovered that dendritic cells, which initiate specific immune responses, can reprogram their genes to improve their immune response

AngioUnrestUHD, will develop and apply new research tools and methods to advance knowledge about the biology of blood vessels in distinct physiological and pathological contexts