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    E.g., 18/04/2025
    E.g., 18/04/2025
    Anagha Jagannathan, Carlos Real Jiménez, Laura Cádiz, Sofía Trigo Anca, Anabel Díaz-Guerra Priego, Miguel Fernández Tocino, Carlos Galán Arriola, Borja Ibáñez, Agustín Clemente Moragón, Sandra Gomez, Ana Devesa, Juan Rene Delgado Cornejo, Danielle Medina-Hernandez, Warren Alexander Skoza, Lucía Pilar López Palomar, Nico Hoffmann, Carlos Caballero Henares and Ángela Pollán García.
    Research
    4 Feb 2025
    JACC CardioOncology: CNIC scientists design an effective treatment strategy to prevent heart injury caused by a class of anticancer drugs

    The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure
    Agustín Clemente-Moragón, Borja Ibáñez, Anabel Díaz-Guerra, Laura Cádiz, Carlos Galán-Arriola, Miguel Fernández-Tocino, Mónica Gómez, Rocío Villena-Gutiérrez, y Eduardo Oliver.
    Research
    16 Apr 2024
    JACC: CardioOncology: CNIC scientists identify therapeutic targets for the prevention of heart injury linked to cancer treatment

    The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity