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    E.g., 02/10/2024
    E.g., 02/10/2024
    Mercedes Ricote, María Piedad Menéndez-Gutiérrez, Jesús Porcuna, Ana Paredes, Vanessa Núñez e Irene Calero.
    Research
    15 Dec 2022
    Blood: RXR, the cell protein that keeps blood stem cells young and fit

    A CNIC team has shown that the  retinoid and unsaturated fatty acid sensor RXR is a key protein in the maintenance of a balanced production of the different types of blood cells
    Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
    Research
    3 Apr 2020
    Nature Communications: CNIC scientists discover a new molecular mechanism that regulates the sentinel cells of the immune system

    Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR
    Publications
    8 Jun 2010
    Identificado el gen RXR-alpha como posible diana terapéutica para el tratamiento de la sepsis por su participación en el control de la inmunidad innata