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    E.g., 28/11/2024
    E.g., 28/11/2024
    Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research
    7 Jun 2021
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart
    Skeletal staining of the inferior limb regions of normal embryos, embryos with a single Meis allele, and an embryo with complete absence of Meis. Embryos with a single copy of Meis lack the fibula and posterior digits (black arrow). Total absence of Meis prevents limb development (white arrow).
    Research
    2 Jun 2021
    Nature Communications: CNIC scientists identify essential factors for limb formation

    The study, published in Nature Communications, reveals that Meis transcription factors are essential for the formation and antero-posterior patterning of the limbs during embryonic development 

    Association between the level of glycosylated hemoglobin and the extent of subclinical atherosclerosis
    Research
    31 May 2021
    JACC: A blood sugar biomarker identifies patients with atherosclerosis and a risk of cardiovascular events

    In an article published in JACC, CNIC scientists report a method for improved ranking of cardiovascular risk in individuals without diabetes
    First biomarker in blood that distinguishes myocarditis from an acute myocardial infarction
    Research
    27 May 2021
    NEJM: The first blood biomarker to distinguish between myocarditis and acute myocardial infarction

    The diagnosis of acute myocarditis is challenging, and the availability of a sensitive and specific early marker of acute myocardial inflammation could have a major impact on its clinical diagnosis
    Sanchez Madrid receives the Santiago Ramón Cajal National Prize in the area of Biology
    About the CNIC
    18 May 2021
    Francisco Sánchez Madrid receives the Santiago Ramón Cajal National Prize in the area of Biology

    The Spanish National Prizes for Research, created in 1982, are the most important awards in Spain in the area of scientific research.
    David Sancho, Carlos del Fresno, Elena Hernández-García, Manuel José Gómez, Francisco Javier Cueto, Salvador Iborra y Paola Brandi.
    Research
    14 May 2021
    JITC: CNIC scientists discover a new strategy to improve cancer immunotherapy

    Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have designed a new strategy to potentiate immunotherapy, the treatment that has revolutionized cancer management
    Sara Martínez Martínez, María José Méndez Olivares, Álvaro Alfayate, , Andrea de la Fuente-Alonso, Miguel R. Campanero, Juan Miguel Redondo y Jesús Vázquez.
    Research
    11 May 2021
    Nature Communications: Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

    Scientists at the CNIC and CSIC have shown that elevated activity of proteins regulated by nitric oxide (NO) causes the aortic disease seen in Marfan Syndrome patients
    Dr. Miguel Torres
    About the CNIC
    10 May 2021
    Dr. Miguel Torres appointed Associate Editor of Science Advances

    Dr. Torres is a member of the European Molecular Biology Organization (EMBO). Dr. Miguel Torres’s scientific research focuses on the regulation of embryonic development and the formation and regeneration of organs.

    Jacky Goetz
    About the CNIC
    28 Apr 2021
    "To do science it is essential to be proactive and not wait for your project to progress on its own"

    Dr. Jacky Goetz works on intravital imaging and biomechanical forces during the progression of tumors.
    3D images obtained in anatomical, functional, and tissue characterization studies performed with the ultrafast cardiac magnetic resonance protocol
    Research
    22 Apr 2021
    JACC: CNIC and Philips develop ultrafast cardiac magnetic resonance technology that analyzes the heart in less than 1 minute

    Ultrafast cardiac magnetic resonance allows precise assessment of heart anatomy and function while reducing healthcare costs and increasing patient comfort