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    E.g., 22/11/2024
    E.g., 22/11/2024
    Ayelén M. Santamans y Guadalupe Sabio
    Research
    19 Jan 2024
    Science Advances: First therapeutic target for preserving heart function in patients with pulmonary hypertension

    A team led by scientists from the CNIC and CNIO has identified a potential therapeutic target that protects the heart in patients with pulmonary hypertension
    Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
    Research
    20 Nov 2023
    JACC: Younger people are more vulnerable to the effects of cardiovascular risk associated with high blood cholesterol and hypertension

    Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough
    La figura muestra imágenes mediante resonancia magnética cardíaca (A y B) y tomografía computarizada (C y D) de un corazón en diástole (A y C) y sístole (B y D) para el cálculo de la función de ambos ventrículos. VD: Ventrículo derecho; VI: Ventrículo izquierdo.
    Research
    12 Dec 2022
    European Journal of Heart Failure: A promising drug treatment for patients with pulmonary hypertension associated with heart disease

    The results of the SPHERE-HF study are published in the European Journal of Heart Failure. SPHERE-HF is a multicenter academic clinical trial led by investigators at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Hospital Clínic de Barcelona
    Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
    About the CNIC
    13 Apr 2021
    JACC: CNIC researchers explain how high blood pressure, the most important cause of disease worldwide, accelerates atherosclerosis

    The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy
    About the CNIC
    25 Jul 2013
    Una terapia génica co-desarrollada por investigadores del CNIC frena con éxito la hipertensión pulmonar en modelos experimentales murinos

    El estudio demuestra que la administración de un tipo de virus capaz de sobre-expresar la proteína SERCA2A es eficaz para el tratamiento de la hipertensión pulmonar en los modelos animales experimentales
    Publications
    25 Jan 2012
    Descubren una posible diana terapéutica para prevenir patologías vasculares incluidas la hipertensión arterial la aterosclerosis