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E.g., 17/12/2025
E.g., 17/12/2025
Héctor Bueno JACARDI
About the CNIC
15 Dec 2025

A new policy paper highlights key areas for advancing data-driven policymaking to curb the rising burden of non-communicable diseases (NCDs), setting the stage for a more effective and equitable healthcare in Europe 

Neutrophils (red) accumulate in the alveoli of a flu-infected lung
Research
2 Dec 2025

An international team has published NeuMap, the first atlas to reveal the global architecture of neutrophils, showing how this “first line of defense” reorganizes to protect, remember, and heal.

Jorge Nicolás Domínguez, Susana Temiño, Morena Raiola, Miquel Sendra y Miguel Torres.
Research
29 May 2025

CNIC researchers have discovered that the heart is formed from two independent cell types that act in synchrony from the onset of gastrulation. This finding could help to better understand the origin of certain congenital heart defects and open up new opportunities in regenerative medicine and tissue bioengineering.

David Sancho, Ignacio Heras-Murillo y Stefanie Wculek.
Research
14 Apr 2025

A study led by the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), in collaboration with the Instituto de Investigación Biomédica de Barcelona (IRB Barcelona), has identified the most effective subtype of dendritic cell for generating immune memory in response to cancer

Juan Pablo Ochoa, Pablo García-Pavía, Laura Lalaguna, Marina López-Olañeta, María Arévalo-Núñez de Arenas y Enrique Lara-Pezzi.
Research
9 Apr 2025

A CNIC team has developed an innovative gene therapy strategy for arrhythmogenic right ventricular cardiomyopathy type 5 (ARVC5), a rare and deadly inherited condition that particularly affects young men

Anagha Jagannathan, Carlos Real Jiménez, Laura Cádiz, Sofía Trigo Anca, Anabel Díaz-Guerra Priego, Miguel Fernández Tocino, Carlos Galán Arriola, Borja Ibáñez, Agustín Clemente Moragón, Sandra Gomez, Ana Devesa, Juan Rene Delgado Cornejo, Danielle Medina-Hernandez, Warren Alexander Skoza, Lucía Pilar López Palomar, Nico Hoffmann, Carlos Caballero Henares and Ángela Pollán García.
Research
4 Feb 2025

The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure

imagen
About the CNIC
30 Sep 2024
Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
Research
19 Sep 2024

A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk

CNIC researchers
Research
30 Aug 2024

Two studies carried out at the CNIC provide key information about a newly identified cardiovascular risk factor, clonal hematopoiesis, and its treatment with the ancient medication colchicine

Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
Research
1 Feb 2024

A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs