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iFlpMosaics is a new technology presented in Nature Methods that allows the modification and study of gene function in mouse models, advancing research on diseases caused by somatic mutations, such as cancer and vascular malformations.

The new project, ‘The Placenta in Maternal and Fetal Cardiovascular Health and Disease’, aims to understand how the placenta influences cardiovascular health in mothers and their children, promising improvements in the prevention and treatment of related diseases

The National Center for Cardiovascular Research (CNIC), and the Health Research Institute of Hospital 12 de Octubre (i+12), representing SERMAS, are actively participating in JACARDI through different pilot projects

A team of scientists from the CNIC and the CSIC has identified a key mechanism in the development of atherosclerosis in patients with the rare genetic disease Hutchinson-Gilford progeria syndrome

Laboratory of Pharmacology and Physiology of the University of Montreal (Canadá)

Globally, cardiovascular diseases due to atherosclerosis – the build-up of plaque in arteries – are the leading cause of death. A new Danish-Spanish research collaboration aims to develop methods to detect atherosclerosis at earlier ages and encourage prevention. Denmark’s Novo Nordisk Foundation has granted up to EUR 23 million to cover the first 2.5 years of the REACT initiative. The initiative is expected to run for 8 years in total

The results, published in JACC, suggest that these factors could be used to predict the risk of developing dilated cardiomyopathy and adapt strategies for patient care and disease detection in genetic carriers of the disease