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Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough

Dr Sancho heads the CNIC Immunobiology Laboratory, whose work focuses on research into the function of dendritic cells and macrophages, as key immune cells that modulate immunity and inflammation, and the use of these cells in immunotherapy in a wide range of diseases

This disease, which can trigger sudden death in elite athletes, is caused by genetic mutations that affect proteins responsible for connecting and coordinating the muscle cells (myocytes) in the myocardium the heart’s muscular wall

The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer

The discovery, published in the journal Immunity, identifies a new therapeutic route for conditions associated with obesity and metabolic syndrome, including cardiovascular disease

A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor

The results of the SPHERE-HF study are published in the European Journal of Heart Failure. SPHERE-HF is a multicenter academic clinical trial led by investigators at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Hospital Clínic de Barcelona

A CNIC study reveals that mutations previously identified in the gene MINDBOMB1 (MIB1) as causing non-compaction cardiomyopathy either provoke this disease or valve defects, depending on their combination with mutations in modifier genes