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    E.g., 22/12/2024
    E.g., 22/12/2024
    Macarena de Andrés Laguillo, Stefano Gambera, Sofía Sánchez Muñoz, Rui Benedito, Irene García González, Mariya Lytvyn Legin, Lourdes García Ortega, Sandra Ruiz García, Susana Ferreira da Rocha, Aroa García Cabero, Luis Diago Domingo.
    Research
    12 Dec 2024
    Nature Methods: CNIC presents iFlpMosaics, an innovative genetic toolkit for the study of gene function

    iFlpMosaics is a new technology presented in Nature Methods that allows the modification and study of gene function in mouse models, advancing research on diseases caused by somatic mutations, such as cancer and vascular malformations.
    ESC_Congress
    About the CNIC
    30 Aug 2024
    Several studies led by the CNIC, informed recommendations included in the newly released 2024 ESC clinical practice guidelines (CPG)
    team photo
    About the CNIC
    11 Jun 2024
    Nucleic Acids Research: A CNIC team has created an innovative tool for the reliable and efficient study of gene function

    iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function
    Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
    Research
    10 Nov 2023
    CIRCULATION RESEARCH: CNIC scientists identify the crucial role of the protein neuregulin-1 in heart development

    Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

    About the CNIC
    3 Oct 2023
    CNIC gets on the move with the Carrera del Corazón fun run
    En primer plano: Emilio Camafeita, Rui Benedito y Macarena Fernández; detrás, de izda. a dcha., Ana Dopazo, Jesús Vázquez, Alberto Benguria, Mariya Lytvyn, Severin Muhleder, Sofía Sánchez, Lourdes García.
    Research
    29 May 2023
    Nature Cardiovascular Research: Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease

    The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer
    Cellular and Molecular Sciences: Describen un nuevo mecanismo que relaciona la inflamación y el remodelado cardiovascular patológico
    Research
    29 Sep 2022
    Cellular and Molecular Sciences: Describing a new mechanism that links inflammation and pathological cardiovascular remodelling
    Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
    Research
    29 Jun 2022
    eLife: Study reveals how Duchenne muscular dystrophy causes heart rhythm problems

    Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    Dr. Cristóbal Belda se convirtió en el nuevo Director del Instituto de Salud Carlos III.
    Research
    11 May 2022
    Cristóbal Belda, Director del ISCIII: “PERTE represents an opportunity to help our country”