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The new study, published in the journal Circulation, opens a new avenue of research into treatments for the atherosclerosis associated with progeria

The elimination of progerin from vascular smooth muscle cells, but not from endothelial cells, prevents the atherosclerosis associated with Hutchinson-Gilford progeria syndrome (HGPS)

CNIC researchers, led by Dr. José Jalife, have made a key discovery about cardiac arrhythmias in Andersen-Tawil syndrome (ATS)

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis

The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances

Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

A CNIC study reveals that mutations previously identified in the gene MINDBOMB1 (MIB1) as causing non-compaction cardiomyopathy either provoke this disease or valve defects, depending on their combination with mutations in modifier genes

The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulation