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    E.g., 25/11/2024
    E.g., 25/11/2024
    Research
    3 Jan 2024
    EMBO Molecular Medicine: Accumulation of the protein versican is the cause of aortic aneurysm in Marfan syndrome

    A team led by scientists at the CNIC and CSIC has found that accumulation of versican in the aortas of Marfan syndrome patients triggers the activation of the nitric oxide pathway through the activation of the the protein AKT

    Sara Martínez Martínez, María José Méndez Olivares, Álvaro Alfayate, , Andrea de la Fuente-Alonso, Miguel R. Campanero, Juan Miguel Redondo y Jesús Vázquez.
    Research
    11 May 2021
    Nature Communications: Inhibition of proteins activated by nitric oxide reverses aortic aneurysm in Marfan syndrome

    Scientists at the CNIC and CSIC have shown that elevated activity of proteins regulated by nitric oxide (NO) causes the aortic disease seen in Marfan Syndrome patients
    Research
    16 Nov 2018
    Nature Communications: Blocking hypertension with antihypertensive drugs prevents the development of a lethal disease

    The study results, published in the journal Nature Communications, identify several proteins implicated in this disease
    Publications
    12 May 2015
    Identificada una mutación asociada al riesgo de aneurisma