Publicaciones seleccionadas
Díez-Díez M, Ramos-Neble BL, de la Barrera J, Silla-Castro JC, Quintas A, Vázquez E, Rey-Martín MA, Izzi B, Sánchez-García L, García-Lunar I, Mendieta G, Mass V, Gómez-López N, Espadas C, González G, Quesada AJ, García-Álvarez A, Fernández-Ortiz A, Lara-Pezzi E, Dopazo A, Sánchez-Cabo F, Ibáñez B, Andrés V, Fuster V, Fuster JJ. Unidirectional association of clonal hematopoiesis with atherosclerosis development. Nat Med (2024) 30:2857-2866
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Zuriaga MA, Yu Z, Matesanz N, Truong B, Ramos-Neble BL, Asensio-López MC, Uddin MM, Nakao T, Niroula A, Zorita V, Amorós-Pérez M, Moro R, Ebert BL, Honigberg MC, Pascual-Figal D, Natarajan P, Fuster JJ. Colchicine prevents accelerated atherosclerosis in TET2-mutant clonal haematopoiesis. 10.1093/eurheartj/ehae546. Eur Heart J (2024) 45:4601-4615
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Zekavat SM, Viana-Huete V, Matesanz N, Jorshery SD, Zuriaga MA, Uddin MM, Trinder M, Paruchuri K, Zorita V, Ferrer-Pérez A, Amorós-Pérez M, Kunderfranco P, Carriero R, Greco CM, Aroca-Crevillen A, Hidalgo A, Damrauer SM, Ballantyne CM, Niroula A, Gibson CJ, Pirruccello J, Griffin G, Ebert BL, Libby P, Fuster V, Zhao H, Ghassemi M, Natarajan P, Bick AG, Fuster JJ, Klarin D. TP53-mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease. TP53-mediated clonal hematopoiesis confers increased risk for incident atherosclerotic disease. Nature Cardiovascular Research (2023) 2:144-158
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Díez-Díez M, Amorós-Pérez M, de la Barrera J, Vázquez E, Quintas A, Pascual-Figal DA, Dopazo A, Sánchez-Cabo F, Kleinman ME, Gordon LB, Fuster V, Andrés V*, Fuster JJ* *co-corresponding authors Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. doi: 10.1007/s11357-022-00607-2. Geroscience (2023) 45:1231-1236
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Tall AR, Fuster JJ. Clonal hematopoiesis in cardiovascular disease and therapeutic implications. Nature Cardiovascular Research (2022) 1:116-124
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Pascual-Figal DA, Bayes-Genis A, Díez-Díez M, Hernández-Vicente Á, Vázquez-Andrés D, de la Barrera J, Vazquez E, Quintas A, Zuriaga MA, Asensio-López MC, Dopazo A, Sánchez-Cabo F, Fuster JJ Clonal Hematopoiesis and Risk of Progression of Heart Failure With Reduced Left Ventricular Ejection Fraction J Am Coll Cardiol (2021) 77:1747-1759
Sánchez-Cabo F, Fuster JJ Clonal haematopoiesis and atherosclerosis: a chicken or egg question? Nat Rev Cardiol (2021) 18:463-464
Fuster JJ, Zuriaga MA, Zorita V, MacLauchlan S, Polackal MN, Viana-Huete V, Ferrer-Perez A, Matesanz N, Herrero-Cervera A, Sano S, Cooper MA, Gonzalez-Navarro H, Walsh K TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity Cell Rep (2020) 33:108326
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Wang Y, Sano S, Yura Y, Ke Z, Sano M, Oshima K, Ogawa H, Horitani K, Min KD, Miura-Yura E, Kour A, Evans MA, Zuriaga MA, Hirschi KK, Fuster JJ, Pietras EM, Walsh K Tet2-mediated clonal hematopoiesis in non-conditioned mice accelerates age-associated cardiac dysfunction JCI Insight (2020) 5:135204
Sano S, Oshima K, Wang Y, MacLauchlan S, Katanasaka Y, Sano M, Zuriaga MA, Yoshiyama M, Goukassian D, Cooper MA, Fuster JJ, Walsh K Tet2-mediated clonal hematopoiesis accelerates experimental heart failure through an IL-1β/NLRP3 inflammasome mechanism J Am Coll Cardiol (2018) 72:875-86
Fuster JJ* and Walsh K* (JJF and KW are co-correspondig authors) Somatic mutations and clonal hematopoiesis: unexpected potential new drivers of age-related cardiovascular disease Circ Res (2018) 122:523-32
Fuster JJ*, MacLauchlan S, Zuriaga MA, Polackal MN, Ostriker AC, Chakraborty R, Wu C-L, Sano S, Muralidharan S, Rius C, Vuong J, Jacob S, Muralidhar V, Robertson AAB, Cooper MA, Andres V, Hirschi KK, Martin KA, Walsh K* (JJF and KW are co-corresponding authors). Clonal hematopoiesis associated with Tet2 deficiency accelerates atherosclerosis development in mice. Science (2017) 355:842-7
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Fuster JJ*, Ouchi N, Gokce N, Walsh K* (JJF and KW are co-corresponding authors) Obesity-Induced Changes in Adipose Tissue Microenvironment and Their Impact on Cardiovascular Disease Circ Res (2016) 118:1786-807
Fuster JJ, Zuriaga MA, Ngo DT, Farb MG, Aprahamian T, Yamaguchi TP, Gokce N, Walsh K Non-canonical Wnt signaling promotes obesity-induced adipose tissue inflammation and metabolic dysfunction Diabetes (2015) 64:1235-48