Protection against blood vessel occlusion in animals with sickle cell anemia after treatment with circadian clock inhibitors. Vessel walls are shown as white lines, neutrophils in yellow, and red blood cells trapped by neutrophils in red.
    Investigación, Publicaciones
    JEM: Neutrophils are less aggressive at night, explaining why nighttime heart attacks cause less damage than daytime events

    A CNIC study reveals that neutrophils—a type of immune cell—are less aggressive at night, explaining why nighttime heart attacks are less severe than those occurring during the day

    Neutrophils (red) accumulate in the alveoli of a flu-infected lung
    Investigación, Publicaciones
    Nature: NeuMap, a pioneering map of neutrophils that redefines their role in health, infection, and inflammation

    An international team has published NeuMap, the first atlas to reveal the global architecture of neutrophils, showing how this “first line of defense” reorganizes to protect, remember, and heal.

    3D reconstruction of the collagen ring (in orange) produced by neutrophils, which forms around wounds in the skin.
    Investigación, Publicaciones
    Nature: CNIC scientists discover a type of immune cell that produces defensive "shields" in the skin

    The discovery, published in Nature, opens the path to new strategies for treating skin diseases and immunological disorders, with special potential for the treatment of inflammation, diabetes, and age-related conditions

    Análisis de muestras humanas y experimentos en animales demuestran que la presencia de mutaciones en el gen p53 en sangre aumenta el riesgo de desarrollar aterosclerosis, la principal causa de enfermedad cardiovascular.
    Investigación, Publicaciones
    Nature Cardiovascular Research: The 'guardian of the genome' protects against cardiovascular disease

    A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor

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