Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
Investigación, Publicaciones

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

Imagen obtenida por microscopía confocal en la que se observa el borde de la cicatriz glial producida tras el infarto cerebral, lo cual dificulta la posterior regeneración de la zona. Este evento es atenuado en gran medida a través del tratamiento con metoprolol intravenoso pre-reperfusión.
Investigación, Publicaciones

Metoprolol, an established drug in the cardiologists armory, protects the brain during a stroke and greatly reduces its consequences


Valentín Fuster
Investigación, Publicaciones

The results of the SECURE trial, coordinated by CNIC were presented in a Hot Line session at the European Society of Cardiology meeting (ESC 2022) in Barcelona and published at the NEJM

Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
Investigación, Publicaciones

Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals

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