Publicaciones seleccionadas

    Aboy-Pardal MCM, Guadamillas MC, Guerrero CR, Català-Montoro M, Toledano-Donado M, Terrés-Domínguez S, Pavón DM, Jiménez-Jiménez V, Jimenez-Carretero D, Zamai M, Folgueira C, Cerezo A, Lolo FN, Nogueiras R, Sabio G, Sánchez-Álvarez M, Echarri A, Garcia R, Del Pozo MA. Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability. Nat Commun (2024) 15:10102
    Repisalud
    Lolo FN, Walani N, Seemann E, Zalvidea D, Pavón DM, Cojoc G, Zamai M, Viaris de Lesegno C, Martínez de Benito F, Sánchez-Álvarez M, Uriarte JJ, Echarri A, Jiménez-Carretero D, Escolano JC, Sánchez SA, Caiolfa VR, Navajas D, Trepat X, Guck J, Lamaze C, Roca-Cusachs P, Kessels MM, Qualmann B, Arroyo M, Del Pozo MA. Caveolin-1 dolines form a distinct and rapid caveolae-independent mechanoadaptation system Nat Cell Biol (2023) 25:120-133
    Link to the full text in Repisalud
    Aboy-Pardal MCM, Jimenez-Carretero D, Terrés-Domínguez S, Pavón DM, Sotodosos-Alonso L, Jiménez-Jiménez V, Sánchez-Cabo F, Pozo MAD. A deep learning-based tool for the automated detection and analysis of caveolae in transmission electron microscopy images. Comput Struct Biotechnol J (2023) 21:224-237
    Link to the full text in Repisalud
    García-García M, Sánchez-Perales S, Jarabo P, Calvo E, Huyton T, Fu L, Ng SC, Sotodosos-Alonso L, Vázquez J, Casas-Tintó S, Görlich D, Echarri A, Del Pozo MA Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP Nat Commun (2022) 13:1174
    Link to the full text in Repisalud
    Lolo FN, Pavón DM, Grande A, Elósegui Artola A, Segatori VI, Sánchez S, Trepat X, Roca-Cusachs P, Del Pozo MA. Caveolae couple mechanical stress to integrin recycling and activation. eLife (2022) 20
    Link to the full text in Repisalud
    Del Pozo MA, Lolo FN, Echarri A Caveolae: Mechanosensing and mechanotransduction devices linking membrane trafficking to mechanoadaptation Curr Opin Cell Biol (2021) 68:113-123
    Bosch M, Sánchez-Álvarez M, Fajardo A, Kapetanovic R, Steiner B, Dutra F, Moreira L, López JA, Campo R, Marí M, Morales-Paytuví F, Tort O, Gubern A, Templin RM, Curson JEB, Martel N, Català C, Lozano F, Tebar F, Enrich C, Vázquez J, Del Pozo MA, Sweet MJ, Bozza PT, Gross SP, Parton RG, Pol A Mammalian lipid droplets are innate immune hubs integrating cell metabolism and host defense Science (2020) 370:eaay8085
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    Albacete-Albacete L, Navarro-Lérida I, López JA, Martín-Padura I, Astudillo AM, Ferrarini A, Van-Der-Heyden M, Balsinde J, Orend G, Vázquez J, Del Pozo M ECM deposition is driven by caveolin-1-dependent regulation of exosomal biogenesis and cargo sorting J Cell Biol (2020) 219:e202006178
    Strippoli R, Sandoval P, Moreno-Vicente R, Rossi L, Battistelli C, Terri M, Pascual-Anton L, Loureiro M, Matteini F, Calvo E, Jimenez-Heffernan JA, Gomez MJ, Jimenez-Jimenez V, Sanchez-Cabo F, Vazquez J, Tripodi M, Lopez-Cabrera M, Del Pozo MA Caveolin1 and YAP drive mechanically induced mesothelial to mesenchymal transition and fibrosis Cell Death Differ (2020) 11:647
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    Echarri A, Pavon DM, Sanchez S, Garcia-Garcia M, Calvo E, Huerta-Lopez C, Velazquez-Carreras D, Viaris de Lesegno C, Ariotti N, Lazaro-Carrillo A, Strippoli R, De Sancho D, Alegre-Cebollada J, Lamaze C, Parton RG, Del Pozo MA An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation Nat Commun (2019) 10:5828
    Link to the full text in Repisalud
    Moreno-Vicente R, Pavon DM, Martin-Padura I, Catala-Montoro M, Diez-Sanchez A, Quilez-Alvarez A, Lopez JA, Sanchez-Alvarez M, Vazquez J, Strippoli R, Del Pozo MA. Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP. Cell Rep (2018) 25:1622-35
    Link to the full text in Repisalud
    Minguet S, Kläsener K, Schaffer AM, Fiala GJ, Osteso-Ibánez T, Raute K, Navarro-Lérida I, Hartl FA, Seidl M, Reth M, Del Pozo MA. Caveolin-1-dependent nanoscale organization of the BCR regulates B cell tolerance Nat Immunol (2017) 18:1150-9
    Sala-Vila A*, Navarro-Lerida I*, Sanchez-Alvarez M, Bosch M, Calvo C, Lopez JA, Calvo E, Ferguson C, Giacomello M, Serafini A, Scorrano L, Enriquez JA, Balsinde J, Parton RG, Vazquez J, Pol A, Del Pozo MA. (*ASV and INL contributed equally) Interplay between hepatic mitochondria-associated membranes, lipid metabolism and caveolin-1 in mice. Sci Rep (2016) 6:27351
    Link to the full text in Repisalud
    Navarro-Lérida I, Pellinen T, Sánchez SA, Guadamillas MC, Wang Y, Mirtti T, Calvo, Del Pozo MA. Rac1 Nucleocytoplasmic Shuttling Drives Nuclear Shape Changes and Tumor Invasion Dev Cell (2015) 32:318-334
    Strippoli R, Loureiro J, Moreno V, Benedicto I, Perez Lozano ML, Barreiro O, Pellinen T, Minguet S, Foronda M, Osteso MT, Calvo E, Vazquez J, Lopez Cabrera M, Del Pozo MA Caveolin-1 deficiency induces a MEK-ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis EMBO Mol Med (2015) 7:102-23
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    Parton RG, Del Pozo MA. Caveolae as plasma membrane sensors, protectors and organizers. Nat Rev Mol Cell Biol (2013) 14:98-112
    Navarro-Lérida I, Sánchez-Perales S, Calvo M, Rentero C, Zheng Y, Enrich C, Del Pozo MA. A palmitoylation switch mechanism regulates Rac1 function and membrane organization. EMBO J (2012) 31:534-51
    Echarri A, Muriel O, Pavón DM, Azegrouz H, Escolar F, Terrón MC, Sanchez-Cabo F, Martínez F, Montoya MC, Llorca O, Del Pozo MA. Caveolar domain organization and trafficking is regulated by Abl kinases and mDia1 J Cell Sci (2012) 125:3097-113
    Goetz JG*, Minguet S*, Navarro-Lérida I, Lazcano JJ, Samaniego R, Calvo E, Tello M, Osteso-Ibáñez T, Pellinen T, Echarri A, Cerezo A, Klein-Szanto AJ, Garcia R, Keely PJ, Sánchez-Mateos P, Cukierman E, Del Pozo MA (JGG and SM contributed equally) Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis Cell (2011) 146:148-63
    Grande-García A, Echarri A, de Rooij J, Alderson NB, Waterman-Storer CM, Valdivielso JM, del Pozo MA. Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. J Cell Biol (2007) 177:683-94

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