Publicaciones seleccionadas

Hamczyk MR*, Nevado RM, Gonzalo P, Andrés-Manzano MJ, Nogales P, Quesada V, Rosado A, Torroja C, Sánchez-Cabo F, Dopazo A, Bentzon JF, López-Otín C, Andrés V*. *co-corresponding authors. Endothelial-to-Mesenchymal Transition Contributes to Accelerated Atherosclerosis in Hutchinson-Gilford Progeria Syndrome. doi: 10.1161/CIRCULATIONAHA.123.065768 Circulation (2024) Aug 29 [Epub ahead of print]

Barettino A, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Guerrero CR, Espinosa FM, Carmona RM, Blanco Y, Dorado B, Torroja C, Sánchez-Cabo F, Quintas A, Benguría A, Dopazo A, García R, Benedicto I*, Andrés V*. *co-corresponding authors. Endothelial YAP/TAZ activation promotes atherosclerosis in a mouse model of Hutchinson-Gilford progeria syndrome. J Clin Invest (2024) Oct 1 [Epub ahead of print]

Benedicto I, Carmona RM, Barettino A, Espinós-Estévez C, Gonzalo P, Nevado RM, de la Fuente-Pérez M, Andrés-Manzano MJ, González-Gómez C, Rolas L, Dorado B, Nourshargh S, Hamczyk MR, Andrés V. Exacerbated atherosclerosis in progeria is prevented by progerin elimination in vascular smooth muscle cells but not endothelial cells. doi:10.1073/pnas.2400752121. Proc Natl Acad Sci U S A (2024) 121:e2400752121
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Díez-Díez M, Amorós-Pérez M, de la Barrera J, Vázquez E, Quintas A, Pascual-Figal DA, Dopazo A, Sánchez-Cabo F, Kleinman ME, Gordon LB, Fuster V, Andrés V*, Fuster JJ* *co-corresponding authors Clonal hematopoiesis is not prevalent in Hutchinson-Gilford progeria syndrome. doi: 10.1007/s11357-022-00607-2. Geroscience (2023) 45:1231-1236
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Macías Á, Díaz-Larrosa JJ, Blanco Y, Fanjul V, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, da Rocha AM, Ponce-Balbuena D, Allan A, Filgueiras-Rama D, Jalife J, Andrés V Paclitaxel mitigates structural alterations and cardiac conduction system defects in a mouse model of Hutchinson-Gilford progeria syndrome Cardiovasc Res (2022) 118:503-516
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Sánchez-López A, Espinós-Estévez C, González-Gómez C, Gonzalo P, Andrés-Manzano MJ, Fanjul V, Riquelme-Borja R, Hamczyk MR, Macías Á, Del Campo L, Camafeita E, Vázquez J, Barkaway A, Rolas L, Nourshargh S, Dorado B, Benedicto I, Andrés V Cardiovascular Progerin Suppression and lamin A Restoration Rescues Hutchinson-Gilford Progeria Syndrome Circulation (2021) 144:1777-1794
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Hamczyk MR, Nevado RM, Barettino A, Fuster V, Andres V Biological Versus Chronological Aging: JACC Focus Seminar J Am Coll Cardiol (2020) 75:919-930
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Fanjul V, Jorge I, Camafeita E, Macías Á, González-Gómez C, Barettino A, Dorado B, Andrés-Manzano MJ, Rivera-Torres J, Vázquez J, López-Otín C, Andrés V Identification of common cardiometabolic alterations and deregulated pathways in mouse and pig models of aging Aging Cell (2020) 19:e13203
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Hamczyk MR, Villa-Bellosta R, Quesada V, Gonzalo P, Vidak S, Nevado RM, Andrés-Manzano MJ, Misteli T, López-Otín C, Andrés V. Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle cells. EMBO Mol Med (2019) 11:e9736
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Del Campo L*, Sanchez-Lopez A*, Salaices M, von Kleeck RA, Exposito E, Gonzalez-Gomez C, Cusso L, Guzman-Martinez G, Ruiz-Cabello J, Desco M, Assoian RK, Briones AM, Andres V. (LDC and ASL contributed equally) Vascular smooth muscle cell-specific progerin expression in a mouse model of Hutchinson-Gilford progeria syndrome promotes arterial stiffness: Therapeutic effect of dietary nitrite. Aging Cell (2019) 18:e12936
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Fernández-Alvira JM, Fuster V, Dorado B, Soberón N, Flores I, Gallardo M, Pocock S, Blasco MA, Andrés V. Short Telomere Load, Telomere Length, and Subclinical Atherosclerosis: The PESA Study. J Am Coll Cardiol (2016) 67:2467-76
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Rivera-Torres J, Calvo CJ, Llach A, Guzman-Martinez G, Caballero R, Gonzalez-Gomez C, Jimenez-Borreguero LJ, Guadix JA, Osorio FG, Lopez-Otin C, Herraiz-Martinez A, Cabello N, Vallmitjana A, Benitez R, Gordon LB, Jalife J, Perez-Pomares JM, Tamargo J, Delpon E, Hove-Madsen L, Filgueiras-Rama D, Andres V. Cardiac electrical defects in progeroid mice and Hutchinson-Gilford progeria syndrome patients with nuclear lamina alterations. Proc Natl Acad Sci U S A (2016) 113:E7250–9
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Chèvre R, González-Granado JM, Megens RT, Sreeramkumar V, Silvestre-Roig C, Molina-Sanchez P, Weber C, Soehnlein O, Hidalgo A*, Andrés V* (VA and AH contributed equally). High-Resolution Imaging of Intravascular Atherogenic Inflammation in Live Mice. Circ Res (2014) 114:770-9
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Fuster JJ, González-Navarro H, Vinué A, Molina P, Andrés-Manzano MJ, Nakayama KI, Nakayama K, Díez-Juan A, Bernad A, Rodríguez C, Martínez-González J, Andrés V. Deficient p27 Phosphorylation at Serine 10 Increases Macrophage Foam Cell Formation and Aggravates Atherosclerosis Through a Proliferation-Independent Mechanism. Arterioscler Thromb Vasc Biol (2011) 31:2455-2463
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González-Navarro H, Abu Nabah Y, Vinué A, Andrés-Manzano MJ, Collado M, Serrano M, Andrés V. p19(ARF) Deficiency Reduces Macrophage and Vascular Smooth Muscle Cell Apoptosis and Aggravates Atherosclerosis. J Am Coll Cardiol (2010) 55:2258-68

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