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Lapuente-Brun E, Moreno-Loshuertos R, Acin-Perez R, Latorre-Pellicer A, Colas C, Balsa E, Perales-Clemente E, Quiros PM, Calvo E, Rodriguez-Hernandez MA, Navas P, Cruz R, Carracedo A, Lopez-Otin C, Perez-Martos A, Fernandez-Silva P, Fernandez-Vizarra E, Enriquez JA Supercomplex Assembly Determines Electron Flux in the Mitochondrial Electron Transport Chain Science (2013) 340:1567-70
Villa-Bellosta R, Rivera J, Osorio FG, Acín-Pérez R, Enríquez JA, López-Otín C, Andrés V. Defective Extracellular Pyrophosphate Metabolism Promotes Vascular Calcification in a Mouse Model of Hutchinson-Gilford Progeria Syndrome that is Ameliorated upon Pyrophosphate Treatment. Circulation (2013) 127:2442-51
Link to the full text in Repisalud
Link to the full text in Repisalud
García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC. Dysfunctional Coq9 Protein Causes Predominant Encephalomyopathy Associated to CoQ Deficiency. Hum Mol Genet (2013) 22:1233-48
Estrada JC, Torres Y, Benguría A, Dopazo A, Roche E, Carrera-Quintanar L, Pérez RA, Enríquez JA, Torres R, Ramírez JC, Samper E*, Bernad A* (ES and AB contributed equally) Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy. Cell Death Dis (2013) 4:e691
Link to the full text in Repisalud
Link to the full text in Repisalud
Segales J, Paz JC, Hernández-Alvarez MI, Sala D, Muñoz JP, Noguera E, Pich S, Palacin M, Enriquez JA, Zorzano A. A form of Mitofusin 2 (Mfn2) lacking the transmembrane domains and the C-terminal end stimulates metabolism in muscle and liver cells. Am J Physiol Endocrinol Metab (2013) 305:E1208-21
Moreno-Loshuertos R, Pérez-Martos A, Fernández-Silva P, Enríquez JA. Length variation in the mouse mitochondrial tRNAA rg DHU loop size promotes OXPHOS functional differences FEBS J (2013) 280:4983-98
Lucas D, Delgado-García JM, Escudero B, Albo C, Aza A, Acín-Pérez R, Torres Y, Moreno P, Enríquez JA, Samper E, Blanco L, Fairén A, Bernad A*, Gruart A* (AB and AG contributed equally) Increased Learning and Brain Long-Term Potentiation in Aged Mice Lacking DNA Polymerase μ. PLoS One (2013) 8:e53243
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Rivera-Torres J*, Acín-Perez R*, Cabezas-Sánchez P, Osorio FG, Gonzalez-Gómez C, Megias D, Cámara C, López-Otín C, Enríquez JA, Luque-García JL, Andrés V (JRT and RAP contributed equally) Identification of mitochondrial dysfunction in Hutchinson-Gilford progeria syndrome through use of stable isotope labeling with amino acids in cell culture. J Proteomics (2013) 91:466-77
Link to the full text in Repisalud
Link to the full text in Repisalud
Balsa E, Marco R, Perales-Clemente E, Szklarczyk R, Calvo E, Landázuri MO, Enríquez JA. NDUFA4 Is a Subunit of Complex IV of the Mammalian Electron Transport Chain Cell Metab (2012) 16:378-86
Quirós PM, Ramsay AJ, Sala D, Fernández-Vizarra E, Rodríguez F, Peinado JR, Fernández-García MS, Vega JA, Enríquez JA, Zorzano A, López-Otín C. Loss of mitochondrial protease OMA1 alters processing of the GTPase OPA1 and causes obesity and defective thermogenesis in mice. EMBO J (2012) 31:2117-33