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    E.g., 21/11/2024
    E.g., 21/11/2024
    Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
    Research
    19 Sep 2024
    JACC: Cardiovascular Imaging: Cardiometabolic risk factors in apparently healthy individuals are linked to altered coronary microcirculation

    A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk
    Figure
    Research
    13 Sep 2024
    The RESILIENCE trial: preventing heart injury caused by anticancer drugs

    RESILIENCE is a clinical trial funded by the European Commission (H2020 Programme) that aims to reduce the prevalence of heart failure in cancer survivors
    About the CNIC
    12 Sep 2024
    Join CNIC through CURE HEART AND BRAIN (COFUND)
    CNIC researchers
    Research
    30 Aug 2024
    Nature Medicine: CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

    Two studies carried out at the CNIC provide key information about a newly identified cardiovascular risk factor, clonal hematopoiesis, and its treatment with the ancient medication colchicine
    Dr. Fuster recibe el premio
    About the CNIC
    27 May 2024
    Dr Valentín Fuster receives the prestigious Lifetime Achievement Award of the World Heart Federation (WHF
    Agustín Clemente-Moragón, Borja Ibáñez, Anabel Díaz-Guerra, Laura Cádiz, Carlos Galán-Arriola, Miguel Fernández-Tocino, Mónica Gómez, Rocío Villena-Gutiérrez, y Eduardo Oliver.
    Research
    16 Apr 2024
    JACC: CardioOncology: CNIC scientists identify therapeutic targets for the prevention of heart injury linked to cancer treatment

    The study, published in the journal JACC: CardioOncology, identifies mitochondrial function and heart metabolism as targets for possible treatments to protect against anthracycline-induced cardiotoxicity
    Ayelén M. Santamans y Guadalupe Sabio
    Research
    19 Jan 2024
    Science Advances: First therapeutic target for preserving heart function in patients with pulmonary hypertension

    A team led by scientists from the CNIC and CNIO has identified a potential therapeutic target that protects the heart in patients with pulmonary hypertension
    Edward Pearce
    Research
    21 Dec 2023
    Edward Pearce: "Prevention is always more economical than treating a heart attack or a heart transplant"

    Johns Hopkins UniversityBloomberg School of Public HealthBaltimore
    Marcos Siguero Álvarez, Luis Luna Zurita, José Luis de la Pompa y Brenda Giselle Flores Garza
    Research
    11 Dec 2023
    Circulation Research: CNIC scientists identify the molecular mechanisms controlling the genes involved in proper formation of the heart valves

    The findings, published in the journal Circulation Research, not only highlight the gene regulatory mechanisms that control valve formation, but also offer clues for future medical advances
    Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
    Research
    10 Nov 2023
    CIRCULATION RESEARCH: CNIC scientists identify the crucial role of the protein neuregulin-1 in heart development

    Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ