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Imágenes del corazón obtenidas mediante resonancia magnética en las que se analizan distintas estructuras de la anatomía y función del corazón: aurículas (paneles A y B), ventrículos (paneles C y D), características del tejido cardiaco (paneles E y F).
Research
3 Mar 2023

The results, published in eClinicalMedicine, have direct implications for clinical practice by providing a list of reference values for a multitude of cardiac parameters used in daily practice

Las células senescentes (mostradas por luminiscencia) aparecieron en el hombro de ratón después de la lesión
Research
19 Dec 2022

The finding provides a basis for mitigating the loss of muscle regenerative capacity in elderly people and for improving muscle repair in young healthy people

Transverse heart sections from wild type mice (WT) and transgenic mice overexpressing beta-3 adrenergic receptor in cardiomyocytes (c-h3tg) after 3 months of aortic stenosis (transaortic constriction, TAC) or control (sham). Hypertrophy after TAC was less severe in the transgenic mice
Research
29 Nov 2022

The experimental study, led by researchers at the CNIC, shows that boosting the expression of this adrenalin receptor in heart cells improves mitochondrial function in the heart

Imagen de histología que muestra la comparación del tamaño del corazón de un ratón normal (izquierda) y un ratón deficiente para la proteína MKK6 (derecha).
Research
9 Aug 2022

A new study published in eLife shows that inhibition of p38γ/δ is a potential therapeutic strategy for the treatment of hypertrophic cardiomyopathy, but that this strategy has yet to be explored because of the lack of specific inhibitors for these p38 family members

An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
Research
17 May 2022

The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart

Alfonso Mora, Ayelén Santamans, Luis Leiva, Guadalupe Sabio, José Antonio Enríquez y Barbara Gonzalez Terán.
Research
24 Nov 2021

The study, published in PLoS Biology, shows for the first time that cardiac metabolism in the postnatal period determines the regulation of metabolism in the whole body

Daño local en las fibras musculares tras el ejercicio. Visualización del daño local en fibras de músculo esquelético (soleous y gastro) de ratón joven tras el ejercicio, mediante la tinción con marcadores de daño local como Filamina C (verde) y Evans Blue (rojo), y los núcleos (en azul) de fibras.
Research
18 Oct 2021

Researchers from the National Center for Cardiovascular Research and the Pompeu Fabra University describe in Science a new mechanism for muscle regeneration after physiological damage

Representative transmurality map from an 3D-upsampled model with a short axis view at high-magnification to illustrate the 3D methodology for transmural-based scar assessment from images obtained with conventional 2D delayed gadolinium-enhanced CMR
Research
28 Sep 2021

This innovative technology may provide an efficient approach in clinical practice after manual or automatic segmentation of myocardial borders in a small number of conventional 2D slices and automatic scar detection


De izquierda a derecha: Enrique Lara-Pezzi, Laura Lalaguna, Laura Ramos, Elena González, María Villalba, Claudia Camarero, Marina López, Betel Olaizola, Ascensión Rey, Carlos Martí, Elísabet Bello y Javier Larrasa
Research
3 Sep 2021

The new findings, published in Circulation Research, could spur the development of new tools for the treatment of cardiac hypertrophy

Dr. Miguel Torres
About the CNIC
10 May 2021

Dr. Torres is a member of the European Molecular Biology Organization (EMBO). Dr. Miguel Torres’s scientific research focuses on the regulation of embryonic development and the formation and regeneration of organs.