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    E.g., 05/04/2025
    E.g., 05/04/2025
    Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
    Research
    1 Feb 2024
    Nature Cardiovascular Research: New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

    A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs
    Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
    Research
    23 Jan 2024
    Circulation Research: APOE genetic variants linked to Alzheimer disease are also associated with the development of subclinical aterosclerosis

    The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis
    David Sancho
    About the CNIC
    19 Jan 2024
    The ImnovAth project, led by Dr. David Sancho, has been selected by the ERC for its Proof of Concept grants

    The ImnovAth project seeks an innovative approach to treat atherosclerosis
    Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
    Research
    20 Nov 2023
    JACC: Younger people are more vulnerable to the effects of cardiovascular risk associated with high blood cholesterol and hypertension

    Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough
    De izda. a dcha.: Gema González, Estefanía Núñez, Sergio Callejas, Juan Carlos Silla, Enrique Lara-Pezzi, Valentín Fuster, Fátima Sánchez Cabo, José Javier Fuster, Ana Dopazo, Borja Ibáñez, Marta Cortés, Alberto Benguría y Antonio Quesada.
    Research
    21 Jun 2023
    European Heart Journal: Atherosclerosis accelerates aging

    A new CNIC study shows that low-grade systemic inflammation triggered by subcinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals
    Enrique Calvo, Jesús Vázquez, Álvaro Alfayate, Estefanía Núñez y José Luis Martín Ventura.
    Research
    28 Mar 2022
    eBiomedicine: Spanish scientists discover a new method for the early detection of subclinical atherosclerosis

    A study published in the journal eBiomedicine identifies new biomarkers that predict the presence of subclinical atherosclerosis
    Bone marrow contributes to the development of atherosclerosis
    Research
    21 Mar 2022
    EHJ: Bone marrow contributes to the development of atherosclerosis

    The new discovery suggests new research avenues toward the discovery of interventions to prevent or arrest atherosclerosis
    Research
    29 Jun 2021
    JACC: Spanish scientists provide the first demonstration that triglycerides are a primary risk factor in atherosclerosis

    A study published in JACC shows that excess circulating triglyceride concentrations are associated with subclinical atherosclerosis and vascular inflammation in individuals with low-to-moderate cardiovascular risk according to standard scores
    Association between the level of glycosylated hemoglobin and the extent of subclinical atherosclerosis
    Research
    31 May 2021
    JACC: A blood sugar biomarker identifies patients with atherosclerosis and a risk of cardiovascular events

    In an article published in JACC, CNIC scientists report a method for improved ranking of cardiovascular risk in individuals without diabetes
    Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
    About the CNIC
    13 Apr 2021
    JACC: CNIC researchers explain how high blood pressure, the most important cause of disease worldwide, accelerates atherosclerosis

    The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy