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E.g., 21/11/2024
E.g., 21/11/2024
María J. Andrés-Manzano, Pilar Gonzalo, Rosa M. Carmona, Cristina González-Gómez, Ana Barettino, Ignacio Benedicto, Vicente Andrés and Ana Dopazo.
Research
7 Oct 2024

A team of scientists from the CNIC and the CSIC has identified a key mechanism in the development of atherosclerosis in patients with the rare genetic disease Hutchinson-Gilford progeria syndrome

De izquierda a derecha: Immunofluorescencia en sección de corazón de pez cebra tras criolesion mostrando células proliferativas (blanco), cardiomiocitos (rojo) núcleos celulares (azul). Imagen de Microscopia electrónica mostrando mitocondrias. Gel Blue Native mostrando bandas correspondientes a supercomplejos formados por CIII (rojo) y CIV (verde).
Research
6 May 2024

Scientists at the CNIC, CIBER, and University of Berne identify the fundamental role of a family of proteins in an essential process for cellular energy production

Daniel Ruiz Iruela, subdirector de Programas Internacionales de Investigación y Relaciones Institucionales del ISCIII; Laura Redondo, técnica de transferencia de tecnología del CNIC; Gemma Gómez, gestora de transferencia de conocimiento del CIBER-ISCIII; Rubén Nieto y Martín León, responsable de Transferencia y responsable de Innovación de la Plataforma ITEMAS, respectivamente, y Francisco Javier García, responsable de la Oficina de Transferencia del Conocimiento (OTC) del ISCIII,
Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
Research
23 Jan 2024

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis

Rafael Yuste
Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
Research
10 Nov 2023

Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

Macaca
Research
18 Apr 2022

The research will provide insights into the development of potential treatments for neurological diseases and obesity, among other human conditions


Bone marrow contributes to the development of atherosclerosis
Research
21 Mar 2022

The new discovery suggests new research avenues toward the discovery of interventions to prevent or arrest atherosclerosis

. 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch.
Research
16 Mar 2022

Scientists at the CNIC have led the development of a new three dimensional ultrasound method that improves the assessment of cardiovascular risk in healthy individuals