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    E.g., 23/11/2024
    E.g., 23/11/2024
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    . 3D model of a femoral artery obtained by real 3D imaging, revealing the location, number, and extent of distinct atherosclerotic plaques. In this sample, three plaques can be discerned (arrows), at the femoral bifurcation and distributed along the superficial branch.
    Research
    16 Mar 2022
    JACC: 3D matrix ultrasound accurately identifies cardiovascular injury in healthy individuals

    Scientists at the CNIC have led the development of a new three dimensional ultrasound method that improves the assessment of cardiovascular risk in healthy individuals
    Representative transmurality map from an 3D-upsampled model with a short axis view at high-magnification to illustrate the 3D methodology for transmural-based scar assessment from images obtained with conventional 2D delayed gadolinium-enhanced CMR
    Research
    28 Sep 2021
    Scientific Reports: 3D mapping of post-infarction scarring increases the prognostic potential of cardiac magnetic resonance imaging

    This innovative technology may provide an efficient approach in clinical practice after manual or automatic segmentation of myocardial borders in a small number of conventional 2D slices and automatic scar detection
    Mapa de T1 obtenido con SACORA y valores promedios
    About the CNIC
    22 Mar 2021
    CNIC and Philips develop a technique that enables assessment of heart anatomy by MRI in only 15 seconds

    The development of this 3D T1 mapping technique, called "SACORA", comes as part of the ongoing collaboration between CNIC and Philips
    About the CNIC
    6 May 2019
    Nature Communications: A newly identified mechanism can be targeted to boost angiogenesis

    Image: In the picture, individual endothelial cells have different fluorescent barcodes and mitogenic stimulations, allowing the non-invasive fate-mapping of their proliferative and migratory behaviours over time.
    About the CNIC
    11 Dec 2017
    eLIFE - Live 3D imaging highlights cellular activity during embryonic heart development
    3D ultrasound of the right carotid artery. An atherosclerotic plaque is visible as a small protrusion (arrow) in the vessel wall of the internal branch of the proximal carotid artery (bottom), close to the bifurcation. In contrast, the surface of the disease-free external branch (top) is smooth (asterisk).
    Research
    24 Jul 2017
    'JACC': 3D visualization of cholesterol plaques improves cardiovascular risk prediction

    CNIC researchers show the value of total atherosclerosis burden for the identification of individuals at risk of cardiovascular disease