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Globally, cardiovascular diseases due to atherosclerosis – the build-up of plaque in arteries – are the leading cause of death. A new Danish-Spanish research collaboration aims to develop methods to detect atherosclerosis at earlier ages and encourage prevention. Denmark’s Novo Nordisk Foundation has granted up to EUR 23 million to cover the first 2.5 years of the REACT initiative. The initiative is expected to run for 8 years in total

Guiomar Mendieta has been awarded the 2023 William W. Parmley Young Author Achievement Award for a paper published in JACC that is considered to an outstanding contribution in the field of atherosclerosis

The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis

Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough

A new CNIC study shows that low-grade systemic inflammation triggered by subcinical atherosclerosis accelerates epigenetic aging in otherwise healthy young individuals

Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals

The project will examine long-term changes in plasma biomarkers of neuronal injury, neuroinflammation, and Alzheimer's disease in participants in the PESA-CNIC-SANTANDER study who have undergone imaging studies to map brain metabolism. The goal of the project is to determine how cardiovascular risk factors during midlife impact brain function