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    E.g., 06/03/2026
    E.g., 06/03/2026
    Imagen de histología que muestra la comparación del tamaño del corazón de un ratón normal (izquierda) y un ratón deficiente para la proteína MKK6 (derecha).
    Research
    9 Aug 2022
    eLife: CNIC scientists uncover opposing roles of p38 proteins in cardiac hypertrophy

    A new study published in eLife shows that inhibition of p38γ/δ is a potential therapeutic strategy for the treatment of hypertrophic cardiomyopathy, but that this strategy has yet to be explored because of the lack of specific inhibitors for these p38 family members
    Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
    Research
    26 Jul 2022
    European Heart Journal: “One change a day makes 365 changes in a year”

    Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals
    Dr. Pablo García-Pavía y Dr. Jesús Gonzalez Mirelis, codirectores del trabajo.
    Research
    22 Jul 2022
    EJHF: Spanish scientists combine genetic and imaging data to improve the treatment of dilated cardiomyopathy

    Genetic screening combined with the detection of fibrosis identifies patients at risk of malignant arrhythmias or developing heart failure with severe complications
    Embrión de ratón con el gen Hoxb1 expresado de forma normal (izquierda) y embrión de ratón donde se expresa fuera de lugar (derecha) por la acción de Oct4
    Research
    14 Jul 2022
    Science Advances: The genes that give the embryonic cells the maximum potential also control the process of their differentiation.
    Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
    Research
    29 Jun 2022
    eLife: Study reveals how Duchenne muscular dystrophy causes heart rhythm problems

    Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”
    Juan Domingo Gisbert
    About the CNIC
    24 Jun 2022
    Juan Domingo Gisbert: "Combining CNIC and BBRC data will allow us to answer questions of great relevance for the prevention of Alzheimer's in healthy subjects"

    Juan Domingo Gispert López, head of the Barcelonaβeta Brain Research Center and CNIC (Spanish National Centre for Cardiovascular Research) researcher
    Una cámara térmica muestra el efecto de la IL-12 sobre la grasa parda en ratón.
    Research
    9 Jun 2022
    Hepatology: Immune cells in the liver regulate body temperature

    A study published in Hepatology demonstrates that the activation of thermogenesis in the livers of obese mice contributes to weight loss and improves diabetes symptoms
    Marta Cortés Canteli teams
    About the CNIC
    18 May 2022
    The BrightFocus Foundation grants an Alzheimer’s Disease Research Standard Award to a CNIC project

    The project will examine long-term changes in plasma biomarkers of neuronal injury, neuroinflammation, and Alzheimer's disease in participants in the PESA-CNIC-SANTANDER study who have undergone imaging studies to map brain metabolism. The goal of the project is to determine how cardiovascular risk factors during midlife impact brain function
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    From left to right: Claudio Badía Careaga, Jesús Vázquez, Enrique Calvo, Elías Herrero Galán, Natalia Vicente, Jorge Alegre Cebollada, Inés Martínez Martín, Carmen Suay Corredera, Diana Velázquez Carreras y Maria Rosaria Pricolo.
    Research
    27 Apr 2022
    Redox Biology: CNIC scientists discover a new mechanism involved in the modulation of heart muscle elasticity

    The results, published in Redox Biology, show the role of conserved cysteine residues in the elastic protein titin in the modulation of the mechanical properties of the myocardium