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A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs

Dr. Carla Rothlin is Dorys McConnell Duberg Professor of Immunobiology and Professor of Pharmacology at the Yale School of Medicine, and co-leader of the Cancer Immunology Programme at Yale Cancer Centre. She studied biochemistry and pharmacology at the University of Buenos Aires, where she also undertook her postgraduate research under the direction of Dr. Ana Belén Elgoyhen, focussing on nicotinic receptors expressed in the inner ear. Later, she completed her doctorate and moved to San Diego to join Dr. Greg Lemke’s laboratory at the Salk Institute for Biological Studies. In 2009, Dr. Rothlin was named Assistant Professor in Immunobiology at Yale Medical School

Scientists at the CNIC and Hospital de la Princesa-UAM have identified profound changes taking place in dendritic cells during antigen presentation to a lymphocyte via intimate contact called an immune synapse

This disease, which can trigger sudden death in elite athletes, is caused by genetic mutations that affect proteins responsible for connecting and coordinating the muscle cells (myocytes) in the myocardium the heart’s muscular wall

The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer

A study by CNIC researchers published in Nature has found that the omega-6 fatty acid gamma-linolenic acid (GLA), present in breast milk, plays an essential role in ensuring the proper functioning of the heart after birth

A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor