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E.g., 04/12/2024
E.g., 04/12/2024
Análisis de muestras humanas y experimentos en animales demuestran que la presencia de mutaciones en el gen p53 en sangre aumenta el riesgo de desarrollar aterosclerosis, la principal causa de enfermedad cardiovascular.
Research
16 Jan 2023

A CNIC study extends the understanding of how acquired mutations in blood cells act as a new cardiovascular risk factor

Descubren un factor clave que protege el corazón tras un infarto
About the CNIC
2 Nov 2022

A new study defines a mechanism that regulates inflammation after a myocardial infarction, opening a path to the use of the receptor

Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
Research
26 Jul 2022

Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals

Marta Cortés Canteli teams
About the CNIC
18 May 2022

The project will examine long-term changes in plasma biomarkers of neuronal injury, neuroinflammation, and Alzheimer's disease in participants in the PESA-CNIC-SANTANDER study who have undergone imaging studies to map brain metabolism. The goal of the project is to determine how cardiovascular risk factors during midlife impact brain function


María García García, Miguel Ángel del Pozo Barriuso, Sara Sánchez Perales, Laura Sotodosos-Alonso, Enrique Calvo, Jesús Vázquez y Asier Echarri
Research
3 Mar 2022

Most biological processes require the import to the cell nucleus of key regulatory factors; one of the most important of these factors is the protein YAP

Research
29 Jun 2021

A study published in JACC shows that excess circulating triglyceride concentrations are associated with subclinical atherosclerosis and vascular inflammation in individuals with low-to-moderate cardiovascular risk according to standard scores

Skeletal staining of the inferior limb regions of normal embryos, embryos with a single Meis allele, and an embryo with complete absence of Meis. Embryos with a single copy of Meis lack the fibula and posterior digits (black arrow). Total absence of Meis prevents limb development (white arrow).
Research
2 Jun 2021

The study, published in Nature Communications, reveals that Meis transcription factors are essential for the formation and antero-posterior patterning of the limbs during embryonic development 

First biomarker in blood that distinguishes myocarditis from an acute myocardial infarction
Research
27 May 2021

The diagnosis of acute myocarditis is challenging, and the availability of a sensitive and specific early marker of acute myocardial inflammation could have a major impact on its clinical diagnosis


Mª Ángeles Zuriaga, Mirian Díez, Fátima Sánchez-Cabo, Ana Dopazo, José Javier Fuster, Ana Quintas y Jorge de la Barrera.
Research
5 Apr 2021

The study, carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia, establishes clonal hematopoiesis as a new cardiovascular risk factor and an important link between aging and cardiovascular disease


3D reconstructions of superior (left) and inferior (right) brain regions, showing regions with lower metabolism associated with the presence of atherosclerotic plaques in the carotid arteries. The color code indicates the magnitude of the observation (yellow, strong association; red, lower association). Gray indicates areas showing no association with carotid plaque presence
Research
15 Feb 2021

Among the modifiable cardiovascular risk factors showing a close association with reduced brain metabolism, the research team found that the most important is hypertension