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    E.g., 05/12/2024
    E.g., 05/12/2024
    Cardiovascular risk factors (particularly metabolic syndrome, insulin resistance, and diabetes) alter coronary microvascular function and increase the risk of atherosclerotic disease, which itself leads to changes in the coronary microcirculation.
    Research
    19 Sep 2024
    JACC: Cardiovascular Imaging: Cardiometabolic risk factors in apparently healthy individuals are linked to altered coronary microcirculation

    A study from CNIC reveals how risk factors and subclinical atherosclerosis affect heart microcirculation in asymptomatic middle-aged individuals. The research, published in JACC: Cardiovascular Imaging, highlights the importance of assessing the heart vessels' ability to regulate blood flow and predict future cardiovascular risk
    CNIC researchers
    Research
    30 Aug 2024
    Nature Medicine: CNIC scientists discover a new cardiovascular risk factor and identify a drug able to reduce its effects

    Two studies carried out at the CNIC provide key information about a newly identified cardiovascular risk factor, clonal hematopoiesis, and its treatment with the ancient medication colchicine
    Dra. Hélène Girouard
    Research
    4 Aug 2024
    Dra. Hélène Girouard: “In alzheimer’s disease, high blood pressure is the main risk factor after age”

    Laboratory of Pharmacology and Physiology of the University of Montreal (Canadá)

    Rebecca F. Gottesman
    Research
    4 Jun 2024
    Rebecca F. Gottesman: “Telling someone their risk of dementia would drop if they treated their high blood pressure would impact them more than the possibility of a heart attack or stroke"

    Stroke Branch Chief at the National Institute of Neurological Disorders and Stroke (NINDS)
    RM cardiaca de un paciente con miocardiopatía dilatada (izquierda) y de un individuo sin cardiopatía (derecha). En el paciente con miocardiopatía dilatada el tamaño del corazón esta incrementado y su capacidad de bombeo está disminuida.
    Research
    19 Apr 2024
    JACC: A new Spanish study provides the first stratification of the risk of developing dilated cardiomyopathy among symptom-free genetic carriers

    The results, published in JACC, suggest that these factors could be used to predict the risk of developing dilated cardiomyopathy and adapt strategies for patient care and disease detection in genetic carriers of the disease

    About the CNIC
    9 Feb 2024
    CNIC Conference Cardiovascular Risk Factors and Brain Health

    The National Center for Cardiovascular Research Carlos III (CNIC) is excited to announce the upcoming edition of the CNIC Conferences
    Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
    Research
    23 Jan 2024
    Circulation Research: APOE genetic variants linked to Alzheimer disease are also associated with the development of subclinical aterosclerosis

    The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis
    Representative results from participants showing atherosclerosis progression (left) and regression (disappearance of plaques, right) in arteries of the neck (carotids) and groin (femorals). Each image pair shows the results of the initial study at baseline and the follow-up study of the same artery 6 years later. The images show representative vascular ultrasound images on the right and 3-dimensional reconstructions on the left.
    Research
    20 Nov 2023
    JACC: Younger people are more vulnerable to the effects of cardiovascular risk associated with high blood cholesterol and hypertension

    Atherosclerosis, previously believed to be an irreversible progressive disease, can be reversed if risk factors are contolled early enough
    Research
    2 Oct 2023
    Diabetes Care: Obesity, high blood pressure, and lipid imbalance trigger a progressive loss of energy generation capacity in the heart

    Scientists at the CNIC have discovered that metabolic cardiovascular risk factors diminish the capacity of the heart to use glucose as an energy source
    The image represent glucose uptake in the brain measured by positron emission tomography in middle-aged individuals with low (top) or high (bottom) sustained cardiovascular risk over 5 years. The colors represent cerebral glucose consumption, with red indicating higher consumption and blue lower consumption
    Research
    31 Aug 2023
    The Lancet Healthy Longevity: Early action to control cardiovascular risk factors preserves brain metabolism

    A study published in The Lancet Healthy Longevity shows that brain metabolism, detected with advanced imaging techniques, declines more sharply in middle-aged people with a sustained high cardiovascular risk over 5 years