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    E.g., 28/11/2025
    E.g., 28/11/2025
    Imagen de histología que muestra la comparación del tamaño del corazón de un ratón normal (izquierda) y un ratón deficiente para la proteína MKK6 (derecha).
    Research
    9 Aug 2022
    eLife: CNIC scientists uncover opposing roles of p38 proteins in cardiac hypertrophy

    A new study published in eLife shows that inhibition of p38γ/δ is a potential therapeutic strategy for the treatment of hypertrophic cardiomyopathy, but that this strategy has yet to be explored because of the lack of specific inhibitors for these p38 family members
    Dr. Pablo García-Pavía y Dr. Jesús Gonzalez Mirelis, codirectores del trabajo.
    Research
    22 Jul 2022
    EJHF: Spanish scientists combine genetic and imaging data to improve the treatment of dilated cardiomyopathy

    Genetic screening combined with the detection of fibrosis identifies patients at risk of malignant arrhythmias or developing heart failure with severe complications
    Embrión de ratón con el gen Hoxb1 expresado de forma normal (izquierda) y embrión de ratón donde se expresa fuera de lugar (derecha) por la acción de Oct4
    Research
    14 Jul 2022
    Science Advances: The genes that give the embryonic cells the maximum potential also control the process of their differentiation.
    Andrés Hidalgo
    About the CNIC
    6 Jul 2022
    Dr. Andrés Hidalgo elected a member of the European Molecular Biology Organization – EMBO

    Through this lifelong honour, new EMBO Members and Associate Members are recognized for their outstanding achievements in the life sciences
    Microfotografía de una monocapa de cardiomiocitos derivados de células madre inducidas a la pluripotencia, representativa de las que se usaron para estudiar los mecanismos de arritmias y el rescate de la función normal por el gen que codifica a la sintrofina-α
    Research
    29 Jun 2022
    eLife: Study reveals how Duchenne muscular dystrophy causes heart rhythm problems

    Investigadores del CNIC  revelan por primera los mecanismos moleculares que subyacen a las arritmias que ocurren en pacientes que padecen “Distrofia Muscular de Duchenne”
    Una cámara térmica muestra el efecto de la IL-12 sobre la grasa parda en ratón.
    Research
    9 Jun 2022
    Hepatology: Immune cells in the liver regulate body temperature

    A study published in Hepatology demonstrates that the activation of thermogenesis in the livers of obese mice contributes to weight loss and improves diabetes symptoms
    An optical section from a ventral view of a mouse embryo at embryonic day E8.0. The section is overlain with a cast of the three-dimensional shape of the forming heart (red) and the incipient circulatory system (purple).
    Research
    17 May 2022
    Nature Cardiovascular Research: A CNIC team creates a dynamic 3D atlas of the formation of the embryonic heart

    The 3D atlas has allowed the scientists to identify the beginning of left–right asymmetry in the heart
    Macaca
    Research
    18 Apr 2022
    Nature: International Team Led by BGI Completes First Whole-Body Cell Atlas of a Non-Human Primate

    The research will provide insights into the development of potential treatments for neurological diseases and obesity, among other human conditions
    Research
    17 Mar 2022
    Circulation: A CNIC study highlights the risks of mitochondrial therapeutic interventions

    The mixing of mitochondrial DNAs (mtDNAs) of two distinct origins can have damaging medium- and long-term effects, according to the results of a new study published in Circulation
    María García García, Miguel Ángel del Pozo Barriuso, Sara Sánchez Perales, Laura Sotodosos-Alonso, Enrique Calvo, Jesús Vázquez y Asier Echarri
    Research
    3 Mar 2022
    Nature Communications: CNIC scientists identify a shuttle protein required for the nuclear import of proteins essential for organ growth and development

    Most biological processes require the import to the cell nucleus of key regulatory factors; one of the most important of these factors is the protein YAP