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    Atrial electroanatomic map of a pig with persistent AFib. The regions colored magenta, purple, and dark blue have high mean FM values. These regions maintain the AFib, and their ablation with a catheter stops the arrhythmia. The squares represent the sites of rotational activity, which are sensitive but not specific to the regions that maintain the fibrillation.
    Research
    12 Sep 2019
    Circulation Research: A new method to improve treatment of atrial fibrillation

    The new study was conducted by investigators at the CNIC, the Hospital Clínico San Carlos in Madrid, and the CiberCV research network and is featured on the cover of the latest edition of the journal Circulation Research

    From left to right: Marta Román, Fernando Domínguez, Laura Padrón-Barthe, Pablo Garcia-Pavia, Giovanna Giovinazzo, Enrique Lara-Pezzi, Demetrio J. Santiago, Javier Larrasa-Alonso
    Research
    5 Sep 2019
    Circulation: Possible treatment breakthrough for the rare disease arrhythmogenic right ventricular cardiomyopathy type 5

    Scientists at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Puerta de Hierro hospital in Majadahonda have found a possible treatment for this disease
    About the CNIC
    16 Jul 2019
    Dr Fuster delves and dissects latest aspects of cardiovascular health and disease

    Dr. Valentín Fuster will be teaching the summer seminar series “Molecular, Clinical & Population Bases of Cardiovascular Disease and Health”, organized by the  International University Menéndez Pelayo (UIMP) and the Icahn School of Medicine at Mount Sinai.
    SRSF3 expression in adult cardiomyocytes. Pink staining shows SRSF3 expression in cell nuclei, which are stained blue. Green staining shows the presence of troponin, a sarcomere protein expressed in cardiomyocytes.
    Research
    4 Jul 2019
    Circulation Research: CNIC scientists identify an essential protein for correct heart contraction and survival

    A new study published in Circulation Research shows that loss of cardiac expression of SRSF3 leads to a critical reduction in the expression of genes related to contraction
    Rui Benedito, Macarena Fernández Chacón, Verónica Casquero García, Federica Lunella y Wen Luo.
    Research
    22 May 2019
    Nature Communications: A new genetic tool to modify and understand gene function

    CNIC scientists have developed a new genetic tool that significantly facilitates the study of gene function in physiological conditions and disease.
    About the CNIC
    6 May 2019
    Nature Communications: A newly identified mechanism can be targeted to boost angiogenesis

    Image: In the picture, individual endothelial cells have different fluorescent barcodes and mitogenic stimulations, allowing the non-invasive fate-mapping of their proliferative and migratory behaviours over time.
    Valentín Fuster
    Research
    23 Apr 2019
    JACC: Early Intervention in preschool is a unique opportunity for promoting a healthy lifestyle

    New study proves educating young children on health and fitness is effective
    Luis Leiva-Vega, Juan Antonio Bernal, Marta Roche-Molina, Ayelén M. Santamans, Valle Montalvo-Romeral, Aránzazu Pintor-Chocano, Rafael Romero-Becerra, Ainoa Caballero, Alfonso Mora, Guadalupe Sabio, Antonia Tomás-Loba, Marta León, Elena Rodríguez, Juan Antonio López, Jesús Vázquez.
    Research
    11 Apr 2019
    Nature: The protein p38gamma identified as a new therapeutic target in liver cancer

    CNIC scientists have shown for the first time that a protein related to cell stress also regulates cell division
    About the CNIC
    3 Apr 2019
    Adiponectin, the hormone that protects women against liver cancer
    • Adiponectin, secreted by adipose tissue, protects against the development of the main form of liver cancer
    • Women produce the hormone in larger quantities than men, and adiponectin release also declines in people with obesity
    • The results open the route to combating a cancer for which there is currently no treatment and that is the fourth cause of death in the world.
    Dr. José María Mendiguren, Director de Servicios Médicos de Banco Santander, Leticia Fernández-Friera, cardióloga del CNIC y del Hospital Universitario HM Montepríncipe, y Dr. Valentín Fuster, Director del CNIC.
    Research
    26 Mar 2019
    JACC: Advanced imaging technology predicts cardiovascular risk from inflammation detected in arteries

    The results, published in JACC, demonstrate the potential of this technology to generate images of the inflammation associated with systemic atherosclerosis; this information will be useful for the study of early stages of this disease and will help to identify individuals who will benefit from early medical intervention