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E.g., 25/11/2024
E.g., 25/11/2024
Experimental design of the study and summary of the results obtained
Research
21 Apr 2020

The study, published today in JACC, shows that activation of the complement system is one of the most characteristic molecular changes taking place in the early stages of the development of atherosclerotic plaques


En la imagen se muestra con un asterisco la presencia de una placa de aterosclerosis avanzada en la carótida común detectada por la técnica de ecografía 3D que no llega a ocasionar una obstrucción significativa de la luz del vaso (es <50%). Se puede comprobar con precisión su extensión en las 3 dimensiones del espacio lo que nos permite detectar cambios en su volumen para determinar si existe un avance de la enfermedad.
Research
7 Apr 2020

A CNIC study published in JACC demonstrates that atheroma plaques extend rapidly in the arteries of asymptomatic individuals aged between 40 and 50 years participating in the PESA-CNIC-Santander study.

Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
Research
3 Apr 2020

Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR

Imágenes de las coroides de ratones control (izquierda) y tras la eliminación de IHH de las células endoteliales (derecha), lo que resulta en una disminución del número de mastocitos (puntos blancos).
Research
20 Mar 2020

Scientists at the CNIC and Weill Cornell Medicine have identified an inflammatory regulatory circuit controlled by a subtype of endothelial cells in the eye

Dr. Filip Swirski
About the CNIC
28 Feb 2020

Dr. Filip Swirski is associate professor at Harvard Medical School and Massachusetts General Hospital (USA) and one of the leading experts on the relationship between sleep and heart disease

María Ángeles Moro
About the CNIC
11 Feb 2020

María Ángeles Moro leads the CNIC's Neurovascular Pathophysiology Laboratory.

Se muestra el corazón y tejidos anejos con la visualización de los vasos linfáticos y las células descendientes del segundo campo cardíaco en rojo.
Research
10 Jan 2020

The international team led by CNIC researchers Drs Miguel Torres and Ghislaine Lioux found that the cardiac lymphatic vasculature does not have a single origin, but is instead formed by cells originating in a variety of tissues

De izda. a dcha.: Asier Echarri, Miguel Ángel del Pozo, Diana Velázquez, Carla Huerta, Sara Sánchez, María García, Raffaele Strippoli, Enrique Calvo, Jorge Alegre-Cebollada.
Research
20 Dec 2019

CNIC scientists have identified the molecular mechanisms that allow our cells to adapt to, protect themselves against, and survive mechanical stress

De izquierda a derecha  José Manuel Alfonso Almazán, Jorge García Quintanilla, Manuel Marina Breysse, José María Lillo Castellano, Julián Pérez Villacastín, David Filgueiras Rama, José Jalife y Nicasio Pérez Castellano.
Research
16 Dec 2019

The study, published in Europace, uses signals from implantable devices—pacemakers and defibrillators—to analyze electrical signals in the heart during episodes of atrial fibrillation

Andrés Hidalgo
Research
10 Dec 2019

The NeutroCure project focuses on reactive oxygen species (ROS), which play central roles in healthy animals, such as redox signalling to regulate cell growth