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    E.g., 22/07/2024
    E.g., 22/07/2024
    About the CNIC
    15 May 2024
    CNIC Co-Leads REACT, an international precision medicine project to transform cardiovascular prevention

    Globally, cardiovascular diseases due to atherosclerosis – the build-up of plaque in arteries – are the leading cause of death. A new Danish-Spanish research collaboration aims to develop methods to detect atherosclerosis at earlier ages and encourage prevention. Denmark’s Novo Nordisk Foundation has granted up to EUR 23 million to cover the first 2.5 years of the REACT initiative. The initiative is expected to run for 8 years in total
    De izquierda a derecha: Immunofluorescencia en sección de corazón de pez cebra tras criolesion mostrando células proliferativas (blanco), cardiomiocitos (rojo) núcleos celulares (azul). Imagen de Microscopia electrónica mostrando mitocondrias. Gel Blue Native mostrando bandas correspondientes a supercomplejos formados por CIII (rojo) y CIV (verde).
    Research
    6 May 2024
    Development Cell: A CNIC study reveals the key role of mitochondrial proteins in cardiac regeneration

    Scientists at the CNIC, CIBER, and University of Berne identify the fundamental role of a family of proteins in an essential process for cellular energy production
    María Jesús Andrés, Carla Espinós (detrás), Rosa M Nevado (delante, al lado de MJA), Miguel de la Fuente, Rosa Carmona, Ana Barettino, Vicente Andrés, Pilar Gonzalo e Ignacio Benedicto.
    Research
    19 Apr 2024
    PNAS: CNIC scientists identify the key cell type for strategies to prevent atherosclerosis in progeria syndrome

    The elimination of progerin from vascular smooth muscle cells, but not from endothelial cells, prevents the atherosclerosis associated with Hutchinson-Gilford progeria syndrome (HGPS)
    RM cardiaca de un paciente con miocardiopatía dilatada (izquierda) y de un individuo sin cardiopatía (derecha). En el paciente con miocardiopatía dilatada el tamaño del corazón esta incrementado y su capacidad de bombeo está disminuida.
    Research
    19 Apr 2024
    JACC: A new Spanish study provides the first stratification of the risk of developing dilated cardiomyopathy among symptom-free genetic carriers

    The results, published in JACC, suggest that these factors could be used to predict the risk of developing dilated cardiomyopathy and adapt strategies for patient care and disease detection in genetic carriers of the disease

    María Linarejos Vera, Gema Mondéjar, Amaia Talavera, Patricia Sánchez, Álvaro Macías, Juan Manuel Ruiz, Francisco M. Cruz, Fernando Martínez de Benito, Juan Antonio Bernal y José Jalife
    Research
    11 Apr 2024
    Circulation Research: New mechanism discovered for the life-threatening arrhythmias in Andersen-Tawil syndrome

    CNIC researchers, led by Dr. José Jalife, have made a key discovery about cardiac arrhythmias in Andersen-Tawil syndrome (ATS)
    El Dr. Valentín Fuster con la Dra. Guiomar Mendieta
    About the CNIC
    10 Apr 2024
    The Journal of the American College of Cardiology garlands the CNIC author of a PESA-CNIC-SANTANDER study

    Guiomar Mendieta has been awarded the 2023 William W. Parmley Young Author Achievement Award for a paper published in JACC that is considered to an outstanding contribution in the field of atherosclerosis
    Rodrigo Fernández Jiménez ha sido galardonado con el Premio Nacional de Investigación para Jóvenes ‘Gabriella Morreale’
    About the CNIC
    15 Mar 2024
    Rodrigo Fernández Jiménez, ‘Gabriella Morreale’ National Youth Research Award winner

    The award honours the quality and relevance of his research work in preventive medicine and on current challenges in the field of cardiology
    About the CNIC
    9 Feb 2024
    CNIC Conference Cardiovascular Risk Factors and Brain Health

    The National Center for Cardiovascular Research Carlos III (CNIC) is excited to announce the upcoming edition of the CNIC Conferences
    Carlos Torroja, Jacob F. Bentzon, Paula Nogales, Laura Carramolino, Vanessa Cumbicus, Daniel Morales, Ana Dopazo, Verónica Labrador y Alberto Benguria
    Research
    1 Feb 2024
    Nature Cardiovascular Research: New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

    A study published in Nature Cardiovascular Research reveals smooth muscle-derived cells as a new target for reducing the size of atherosclerotic plaque. The results open up new avenues for the design of treatments to enhance the beneficial effect of cholesterol-lowering drugs
    Catarina Tristão Pereira, Enrique Lara Pezzi, Raquel Toribio Fernández, Borja Ibáñez, Valentín Fuster, Sergio Callejas, Marta Cortés Canteli, Ana Dopazo, Pilar Martín, Inés García Lunar e Irene Fernández Nueda.
    Research
    23 Jan 2024
    Circulation Research: APOE genetic variants linked to Alzheimer disease are also associated with the development of subclinical aterosclerosis

    The most potent genetic risk factor for Alzheimer disease, APOE4, is associated with an elevated risk of developing subclinical atherosclerosis in middle age, whereas the Alzheimer-protective variant of the same gene, APOE2, protects against subclinical atherosclerosis