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    E.g., 21/04/2025
    E.g., 21/04/2025
    Research
    13 Oct 2020
    Angewandte Chemie International Edition: Controlling the speed of enzyme motors brings biomedical applications of nanorobots closer

    A new study, published in the journal Angewandte Chemie International Edition, describes a tool for modulating nanomotors powered by enzymes, broadening their potential biomedical and environmental applications
    Research
    29 Sep 2020
    JACC: CNIC scientists design an algorithm for personalized cardiovascular risk estimation in healthy people

    The study, published in JACC, forms part of the PESA-CNIC-SANTANDER project, led by Dr Valentín Fuster
    Research
    17 Sep 2020
    Nature Metabolism: CNIC researchers discover a mechanism allowing immune cells to regulate obesity

    The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes
    Research
    16 Sep 2020
    Cell: CNIC researchers discover a cell-cleaning system that keeps hearts healthy

    The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart
    Research
    30 Jul 2020
    Nature: Scientists at the CNIC and IIS Princesa decipher a key mechanism in hypoxia

    The study, published in Nature, shows that sodium controls hypoxic signaling in the mitochondrial respiratory chain
    Alfonso Mora, María Elena Rodríguez Andrés, Guadalupe Sabio, Alejandro Rosell, Cintia Folgueira and Luis Leiva-Vega.
    Research
    30 Jun 2020
    PNAS: Scientists discover a new mechanism controlling liver cancer development

    CNIC scientists have designed an animal model to study the development of liver cancer caused by bile acids
    Research
    4 Jun 2020
    Science Advances: CNIC scientists discover a system essential for limb formation during embryonic development

    Published in Science Advances, the study shows that malfunctioning of this system leads to congenital deformities
    Experimental design of the study and summary of the results obtained
    Research
    21 Apr 2020
    JACC: Spanish scientists identify a biomarker that detects atherosclerosis before the appearance of symptoms

    The study, published today in JACC, shows that activation of the complement system is one of the most characteristic molecular changes taking place in the early stages of the development of atherosclerotic plaques
    En la imagen se muestra con un asterisco la presencia de una placa de aterosclerosis avanzada en la carótida común detectada por la técnica de ecografía 3D que no llega a ocasionar una obstrucción significativa de la luz del vaso (es <50%). Se puede comprobar con precisión su extensión en las 3 dimensiones del espacio lo que nos permite detectar cambios en su volumen para determinar si existe un avance de la enfermedad.
    Research
    7 Apr 2020
    JACC: Atherosclerosis progresses rapidly in healthy people from the age of 40

    A CNIC study published in JACC demonstrates that atheroma plaques extend rapidly in the arteries of asymptomatic individuals aged between 40 and 50 years participating in the PESA-CNIC-Santander study.
    Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
    Research
    3 Apr 2020
    Nature Communications: CNIC scientists discover a new molecular mechanism that regulates the sentinel cells of the immune system

    Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR