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    E.g., 26/11/2024
    E.g., 26/11/2024
    Scheme of a cMyBP-C region in which mutations cause amino-acid changes that alter the mechanical properties of the protein. The positions of the affected amino acids are shown in red.
    Research
    7 Jun 2021
    ACS Nano: CNIC scientists describe a possible disease-causing mechanism in hypertrophic cardiomyopathy

    A team led by Dr. Jorge Alegre-Cebollada has shown, for the first time, an association between hypertrophic cardiomyopathy and mechanical alterations to a component of the contractile machinery of the heart
    Dr. Miguel Torres
    About the CNIC
    10 May 2021
    Dr. Miguel Torres appointed Associate Editor of Science Advances

    Dr. Torres is a member of the European Molecular Biology Organization (EMBO). Dr. Miguel Torres’s scientific research focuses on the regulation of embryonic development and the formation and regeneration of organs.

    Jacky Goetz
    About the CNIC
    28 Apr 2021
    "To do science it is essential to be proactive and not wait for your project to progress on its own"

    Dr. Jacky Goetz works on intravital imaging and biomechanical forces during the progression of tumors.
    3D reconstructions of superior (left) and inferior (right) brain regions, showing regions with lower metabolism associated with the presence of atherosclerotic plaques in the carotid arteries. The color code indicates the magnitude of the observation (yellow, strong association; red, lower association). Gray indicates areas showing no association with carotid plaque presence
    Research
    15 Feb 2021
    JACC: Spanish scientists uncover early links between cardiovascular risk and brain metabolism

    Among the modifiable cardiovascular risk factors showing a close association with reduced brain metabolism, the research team found that the most important is hypertension
    Manuel José Gómez, Ester Marina-Zárate, Almudena Ramiro, Ana Dopazo, Irene Fernández-Delgado, Francisco Sánchez-Madrid y Diego Calzada-Fraile
    Research
    3 Feb 2021
    Science Advances: Spanish scientists identify a mechanism through which dendritic cells improve their antiviral and immune-activation abilities

    Researchers at the CNIC have discovered that dendritic cells, which initiate specific immune responses, can reprogram their genes to improve their immune response
    About the CNIC
    10 Dec 2020
    The 'ProtMechanics-Live' project, led by Dr. Jorge Alegre, awarded ERC Consolidator funding in the ERC-2020-COG call

    'ProtMechanics-Live' is based on unique expertise in protein mechanics and engineering, biophysics, biochemistry and cardiovascular biology and will allow to investigate protein mechanics for the first time in its functionally relevant physiological context
    About the CNIC
    10 Dec 2020
    'AngioUnrestUHD', led by Dr. Rui Benedito, awarded ERC Consolidator funding in the ERC-2020-COG call for proposals

    AngioUnrestUHD, will develop and apply new research tools and methods to advance knowledge about the biology of blood vessels in distinct physiological and pathological contexts
    Research
    29 Sep 2020
    JACC: CNIC scientists design an algorithm for personalized cardiovascular risk estimation in healthy people

    The study, published in JACC, forms part of the PESA-CNIC-SANTANDER project, led by Dr Valentín Fuster
    Research
    17 Sep 2020
    Nature Metabolism: CNIC researchers discover a mechanism allowing immune cells to regulate obesity

    The results published in Nature Metabolism could be useful to design new treatments for the obese and overweight, and for some associated pathologies, including fatty liver disease and type 2 diabetes
    Research
    16 Sep 2020
    Cell: CNIC researchers discover a cell-cleaning system that keeps hearts healthy

    The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart