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    E.g., 25/11/2024
    E.g., 25/11/2024
    Jesús Vázquez, Jacob Fog Bentzon, Emilio Camafeita y Esmeralda Lewis.
    About the CNIC
    13 Apr 2021
    JACC: CNIC researchers explain how high blood pressure, the most important cause of disease worldwide, accelerates atherosclerosis

    The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy
    About the CNIC
    10 Dec 2020
    The 'ProtMechanics-Live' project, led by Dr. Jorge Alegre, awarded ERC Consolidator funding in the ERC-2020-COG call

    'ProtMechanics-Live' is based on unique expertise in protein mechanics and engineering, biophysics, biochemistry and cardiovascular biology and will allow to investigate protein mechanics for the first time in its functionally relevant physiological context
    About the CNIC
    10 Dec 2020
    'AngioUnrestUHD', led by Dr. Rui Benedito, awarded ERC Consolidator funding in the ERC-2020-COG call for proposals

    AngioUnrestUHD, will develop and apply new research tools and methods to advance knowledge about the biology of blood vessels in distinct physiological and pathological contexts
    Research
    6 Oct 2020
    JACC: Vigorous exercise, spongy heart

    CNIC scientists have shown that vigorous physical exercise is linked to "noncompaction" of the heart, causing it to acquire a spongy appearance.
    Research
    4 May 2020
    Cardiovascular Research: Spanish scientists discover how the flu virus injures the heart

    The study shows that the replication of flu virus particles infecting the heart blocks the transmission of cardiac electrical impulses
    Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
    Research
    3 Apr 2020
    Nature Communications: CNIC scientists discover a new molecular mechanism that regulates the sentinel cells of the immune system

    Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR
    De izquierda a derecha José Manuel Alfonso Almazán, Jorge García Quintanilla, Manuel Marina Breysse, José María Lillo Castellano, Julián Pérez Villacastín, David Filgueiras Rama, José Jalife y Nicasio Pérez Castellano.
    Research
    16 Dec 2019
    Europace: Personalized medicine for atrial fibrillation

    The study, published in Europace, uses signals from implantable devices—pacemakers and defibrillators—to analyze electrical signals in the heart during episodes of atrial fibrillation
    : Blood vessel duplications in the inflamed intestinal mucosa of a mouse with colitis.
    Research
    3 Dec 2019
    EMBO Molecular Medicine: Inhibiting a protease could improve the treatment of inflammatory bowel disease

    Scientists at the CNIC and CSIC have identified a function of a protease that could be the future target of drugs to treat inflammatory bowel disease
    Atrial electroanatomic map of a pig with persistent AFib. The regions colored magenta, purple, and dark blue have high mean FM values. These regions maintain the AFib, and their ablation with a catheter stops the arrhythmia. The squares represent the sites of rotational activity, which are sensitive but not specific to the regions that maintain the fibrillation.
    Research
    12 Sep 2019
    Circulation Research: A new method to improve treatment of atrial fibrillation

    The new study was conducted by investigators at the CNIC, the Hospital Clínico San Carlos in Madrid, and the CiberCV research network and is featured on the cover of the latest edition of the journal Circulation Research

    Pilar Gonzalo, Rosa Nevado, Ricardo Villa-Bellosta, Magda R. Hamczyk, María J. Andrés-Manzano, and Vicente Andrés.
    Research
    12 Mar 2019
    EMBO Molecular Medicine: CNIC scientists discover a new therapeutic target for blocking early atherosclerosis in progeria

    This new results, published in EMBO Molecular Medicine, identify a possible therapeutic target for this genetic disease