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    E.g., 30/03/2025
    E.g., 30/03/2025
    Anagha Jagannathan, Carlos Real Jiménez, Laura Cádiz, Sofía Trigo Anca, Anabel Díaz-Guerra Priego, Miguel Fernández Tocino, Carlos Galán Arriola, Borja Ibáñez, Agustín Clemente Moragón, Sandra Gomez, Ana Devesa, Juan Rene Delgado Cornejo, Danielle Medina-Hernandez, Warren Alexander Skoza, Lucía Pilar López Palomar, Nico Hoffmann, Carlos Caballero Henares and Ángela Pollán García.
    Research
    4 Feb 2025
    JACC CardioOncology: CNIC scientists design an effective treatment strategy to prevent heart injury caused by a class of anticancer drugs

    The study, published in JACC: CardioOncology, shows that administration of the SGLT2 inhibitor empagliflozin to pigs receiving anthracyclines preserves mitochondrial function, improves myocardial energetics, and prevents degenerative changes in heart structure
    Macarena de Andrés Laguillo, Stefano Gambera, Sofía Sánchez Muñoz, Rui Benedito, Irene García González, Mariya Lytvyn Legin, Lourdes García Ortega, Sandra Ruiz García, Susana Ferreira da Rocha, Aroa García Cabero, Luis Diago Domingo.
    Research
    12 Dec 2024
    Nature Methods: CNIC presents iFlpMosaics, an innovative genetic toolkit for the study of gene function

    iFlpMosaics is a new technology presented in Nature Methods that allows the modification and study of gene function in mouse models, advancing research on diseases caused by somatic mutations, such as cancer and vascular malformations.
    imagen
    About the CNIC
    30 Sep 2024
    CNIC Joins the 2024 Heart Race
    ESC_Congress
    About the CNIC
    30 Aug 2024
    Several studies led by the CNIC, informed recommendations included in the newly released 2024 ESC clinical practice guidelines (CPG)
    team photo
    About the CNIC
    11 Jun 2024
    Nucleic Acids Research: A CNIC team has created an innovative tool for the reliable and efficient study of gene function

    iSuRe-HadCre promises to become an essential tool for biomedical research using mouse models to modify and understand gene function
    Neuregulin-1 induces changes in actin filaments during ventricular maturation. Actinin staining of a mouse embryo heart reveals a striated actin pattern corresponding to mature trabecular sarcomeres (green). The magnified view shows the differences in luminosity that distinguish the more organized actin filaments of the trabecular myocardium from the less organized compact layer
    Research
    10 Nov 2023
    CIRCULATION RESEARCH: CNIC scientists identify the crucial role of the protein neuregulin-1 in heart development

    Neuregulin-1 (Nrg1) plays an essential role in the transformation of the heart from its delicate primordial structure into the powerful beating mature organ 

    About the CNIC
    3 Oct 2023
    CNIC gets on the move with the Carrera del Corazón fun run
    la Dra. Mercedes Ricote y la Dra. Ana Paredes
    About the CNIC
    29 Sep 2023
    Researcher Ana Paredes wins the International Birnstiel Award 2023

    The Spanish National Centre for Cardiovascular Research (CNIC) researcher Dr Ana Paredes has won the International Birnstiel Award 2023
    En primer plano: Emilio Camafeita, Rui Benedito y Macarena Fernández; detrás, de izda. a dcha., Ana Dopazo, Jesús Vázquez, Alberto Benguria, Mariya Lytvyn, Severin Muhleder, Sofía Sánchez, Lourdes García.
    Research
    29 May 2023
    Nature Cardiovascular Research: Scientists identify how some angiogenic drugs used to treat cancer and heart disease cause vascular disease

    The new study, published in Nature Cardiovascular Research, will help to select the most effective and safe way to modulate angiogenesis in ischemic tissues or in cancer
    Dr. García Pavía
    Research
    21 May 2023
    NEJM: A Spanish team presents the first pharmacological treatment able to improve cardiac function in stiff-heart syndrome

    The team led by Dr. Pablo García-Pavía, based at the CNIC and Hospital Puerta de Hierro, has published the first study of a drug able to remove amyloid deposits from the heart