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    E.g., 16/09/2025
    E.g., 16/09/2025
    Cells use two mechanisms to detect force: one gradual and progressive mediated by newly identified large membrane depressions called dolines (left); the other abrupt, activated above a certain threshold, and mediated by minute membrane invaginations called caveolae (right).
    Research
    23 Dec 2022
    Nature Cell Biology: A CNIC study shows that cells possess 2 mechanisms to allow them to respond to different force ranges

    A study published in Nature Cell Biology confirms that caveolae are essential for the mechanical responses of tissues subject to large mechanical forces (such as muscle, heart, blood vessels, and fat), whereas larger membrane depressions (termed 'dolines') are important for the response to weak or medium-strength forces
    La figura muestra imágenes mediante resonancia magnética cardíaca (A y B) y tomografía computarizada (C y D) de un corazón en diástole (A y C) y sístole (B y D) para el cálculo de la función de ambos ventrículos. VD: Ventrículo derecho; VI: Ventrículo izquierdo.
    Research
    12 Dec 2022
    European Journal of Heart Failure: A promising drug treatment for patients with pulmonary hypertension associated with heart disease

    The results of the SPHERE-HF study are published in the European Journal of Heart Failure. SPHERE-HF is a multicenter academic clinical trial led by investigators at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and Hospital Clínic de Barcelona
    Research
    3 Nov 2022
    Nature Cardiovascular Research: CNIC scientists identify the cause of arrhythmias and sudden death in Andersen-Tawil syndrome type 1

    CNIC scientists have identified a molecular mechanism that accounts for the arrhythmias, skeletal muscle weakness, and periodic paralysis in patients with this rare disease

    Cellular and Molecular Sciences: Describen un nuevo mecanismo que relaciona la inflamación y el remodelado cardiovascular patológico
    Research
    29 Sep 2022
    Cellular and Molecular Sciences: Describing a new mechanism that links inflammation and pathological cardiovascular remodelling
    About the CNIC
    19 Sep 2022
    El Dr. Valentín Fuster, receives Prestigious Award from Cardiovascular Research Foundation

    CNIC's leader have been recognized for his exceptional career achievements at the 34th annual conference
    Los adolescentes que duermen menos de 8 horas tienen más probabilidades de tener sobrepeso u obesidad
    Research
    29 Aug 2022
    Insufficient sleep in teenagers is associated with overweight and obesity

    Excess weight and metabolic syndrome are associated with cardiovascular disease, suggesting that health promotion programs in schools should teach good sleep habits
    Valentín Fuster
    Research
    26 Aug 2022
    NEJM: The polypill reduces cardiovascular mortality by 33% in patients treated after myocardial infarction

    The results of the SECURE trial, coordinated by CNIC were presented in a Hot Line session at the European Society of Cardiology meeting (ESC 2022) in Barcelona and published at the NEJM

    Participants who followed the TANSNIP-PESA program (orange line) showed an improvement in lifestyle measures and cardiovascular health compared with participants in the control group (who did not participate in the intervention; blue line). The Y-axis shows changes in the Fuster -BEWAT lifestyle and cardiovascular risk score with respect to the baseline value.
    Research
    26 Jul 2022
    European Heart Journal: “One change a day makes 365 changes in a year”

    Adherence to a workplace cardiovascular health-promotion program improves lifestyle and risk factors in healthy individuals
    Andrés Hidalgo
    About the CNIC
    6 Jul 2022
    Dr. Andrés Hidalgo elected a member of the European Molecular Biology Organization – EMBO

    Through this lifelong honour, new EMBO Members and Associate Members are recognized for their outstanding achievements in the life sciences
    Juan Domingo Gisbert
    About the CNIC
    24 Jun 2022
    Juan Domingo Gisbert: "Combining CNIC and BBRC data will allow us to answer questions of great relevance for the prevention of Alzheimer's in healthy subjects"

    Juan Domingo Gispert López, head of the Barcelonaβeta Brain Research Center and CNIC (Spanish National Centre for Cardiovascular Research) researcher