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E.g., 25/08/2024
Alfonso Mora, María Elena Rodríguez Andrés, Guadalupe Sabio, Alejandro Rosell, Cintia Folgueira and Luis Leiva-Vega.
Research
30 Jun 2020

CNIC scientists have designed an animal model to study the development of liver cancer caused by bile acids

Microscopía confocal mostrando un macrófago peritoneal de un ratón deficiente en RXR, donde se observa un alto contenido de lípidos (verde) dentro de vesículas ácidas (rojo).
Research
3 Apr 2020

Published in Nature Communications, the study suggests that it may be possible to regulate the number and activity of these macrophages with drugs that modulate the nuclear receptor RXR

Luis Leiva-Vega, Juan Antonio Bernal, Marta Roche-Molina, Ayelén M. Santamans, Valle Montalvo-Romeral, Aránzazu Pintor-Chocano, Rafael Romero-Becerra, Ainoa Caballero, Alfonso Mora, Guadalupe Sabio, Antonia Tomás-Loba, Marta León, Elena Rodríguez, Juan Antonio López, Jesús Vázquez.
Research
11 Apr 2019

CNIC scientists have shown for the first time that a protein related to cell stress also regulates cell division

About the CNIC
3 Apr 2019
  • Adiponectin, secreted by adipose tissue, protects against the development of the main form of liver cancer
  • Women produce the hormone in larger quantities than men, and adiponectin release also declines in people with obesity
  • The results open the route to combating a cancer for which there is currently no treatment and that is the fourth cause of death in the world.
Borja Ibáñez, Carlos Galán, Rodrigo Fernández, Eduardo Oliver, Gonzalo Pizarro, Manuel Lobo, Jean Paul Vilchez Tschischke, Antonio de Molina-Iracheta, Rocío Villena y Javier Sánchez-González
Research
19 Feb 2019

The results have implications for patient prognosis, since detection of this marker can prompt intervention to prevent irreversible damage


La Dra. Guadalupe Sabio en su laboratorio.
About the CNIC
25 Oct 2017

Dr. Sabio leads a research group at the Carlos III National Cardiovascular Research Center (CNIC) whose main line of research are diseases related to obesity, like cardiovascular diseases, diabetes and liver cancer.


The CNIC research team. From left to right: Andrés Hidalgo, David Sancho, Sarai Martínez-Cano, Salvador Iborra, Elena Priego, Michel Enamorado, and Juan Antonio Quintana.
Research
17 Jul 2017

The study, published in Nature Communications, demonstrates that tissue-resident and circulating memory T cells cooperate in anti-tumor immunity


Ángel Álvarez Prado, Prof. Jesús Vázquez, Juan Antonio López del Olmo, Dra. Almudena Ramiro y Dra. Virginia G. de Yébenes
Research
22 Feb 2017

Every year 400000 people are diagnosed with lymphoma, and 200000 people die from the consequences of this blood cancer

Publications
8 Sep 2015

Investigadores del Centro Nacional de Investigaciones Cardiovasculares (CNIC) han descubierto por primera vez un mecanismo de protección contra el desarrollo de cáncer asociado a procesos inflamatorios