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The new insight supports the need to keep both LDL cholesterol and blood pressure low throughout life by healthy diet choices, weight control, exercise, and, when needed, by drug therapy

The study, carried out at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) and the Hospital Universitario Virgen de Arrixaca in Murcia, establishes clonal hematopoiesis as a new cardiovascular risk factor and an important link between aging and cardiovascular disease

AngioUnrestUHD, will develop and apply new research tools and methods to advance knowledge about the biology of blood vessels in distinct physiological and pathological contexts

Research could change standard of care protocols to prevent clotting associated with coronavirus

The international team led by CNIC researchers Drs Miguel Torres and Ghislaine Lioux found that the cardiac lymphatic vasculature does not have a single origin, but is instead formed by cells originating in a variety of tissues

The project aims to study how certain mutations acquired in blood cells and traditionally associated with a high risk of developing leukemia can also contribute to the development of cardiovascular disease and become a new and independent cardiovascular risk factor to classical factors

The expression on lymphocytes of the molecule CD69 inversely predicts the development of subclinical (symptom-free) atherosclerosis independently of classical cardiovascular risk factors

Dr. Göttgens gave the conference "Cellular States, Differentiation Trajectories and Regulatory Networks of Blood Cell Development" at the CNIC Seminar cycle, invited by Dr. Miguel Manzanares.